Evidence map›Paper›PMID 32955944›Full record

ReviewAnnual review of genetics2020

A Field Guide to Eukaryotic Transposable Elements.

Jonathan N Wells, Cédric Feschotte

Open access · bronzeAbstract readReview
In one paragraph

Review in Annual review of genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 404 papers.

0numbers the graph read from it
0cells of the map it votes in
404citing papers in PubMed
65.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

404 citing papers in PubMed, 655 citations in OpenAlex.

  1. Review
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  8. Review
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  16. Review
  17. Article
  18. DNA-bound avian R2 non-LTR retrotransposon protein recruits a second R2 protein for genome-protective second-strand nicking.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  19. Article
  20. Article

344 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jonathan N WellsDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14850; email: jnw72@cornell.edu, cf458@cornell.edu.
Cédric FeschotteDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14850; email: jnw72@cornell.edu, cf458@cornell.edu.
Cornell University · US

Funding

Genomic and Physiological Impact of Transposable Elements.R35GM122550 · NIGMS · CORNELL UNIVERSITY · PI Cedric Feschotte · 2017 to 2026
$4.4M
Connecting transposable elements and regulatory innovation using ENCODE dataU01HG009391 · NHGRI · WASHINGTON UNIVERSITY · PI COHEN, BARAK A, FESCHOTTE, CEDRIC · 2017 to 2021
$2.4M
Endogenous Retroviruses Co-Opted for Immune DefensesR01GM112972 · NIGMS · UNIVERSITY OF UTAH · PI FESCHOTTE, CEDRIC · 2015 to 2017
$804k
NHGRI NIH HHS U01 HG009391NIGMS NIH HHS R01 GM112972NIGMS NIH HHS R35 GM122550
6 · The paper itself

Abstract

Transposable elements (TEs) are mobile DNA sequences that propagate within genomes. Through diverse invasion strategies, TEs have come to occupy a substantial fraction of nearly all eukaryotic genomes, and they represent a major source of genetic variation and novelty. Here we review the defining features of each major group of eukaryotic TEs and explore their evolutionary origins and relationships. We discuss how the unique biology of different TEs influences their propagation and distribution within and across genomes. Environmental and genetic factors acting at the level of the host species further modulate the activity, diversification, and fate of TEs, producing the dramatic variation in TE content observed across eukaryotes. We argue that cataloging TE diversity and dissecting the idiosyncratic behavior of individual elements are crucial to expanding our comprehension of their impact on the biology of genomes and the evolution of species.

Indexed as

AnimalsDNA Transposable ElementsEukaryotaEvolution, MolecularGenetic VariationGenomeHumansDNA Transposable Elementsgenome evolutionretrotransposonstransposable element originstransposition mechanismstransposons

Identifiers

PMID32955944
PMCPMC8293684
OpenAlexW3087081867

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.