Evidence map›Paper›PMID 32955878›Full record

ArticleJournal of the American Chemical Society2020

A Near-Infrared Fluorogenic Pyrrole-Imidazole Polyamide Probe for Live-Cell Imaging of Telomeres.

Yutaro Tsubono, Yusuke Kawamoto, Takuya Hidaka, Ganesh N Pandian, Kaori Hashiya, Toshikazu Bando, Hiroshi Sugiyama

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Recent Advances in Organelle-Targeted Fluorescent Probes.Molecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yutaro TsubonoDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
Yusuke KawamotoDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.ORCID 0000-0001-9655-8241
Takuya HidakaDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
Ganesh N PandianInstitute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University, Sakyo, Kyoto 6060-8501, Japan.
Kaori HashiyaDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
Toshikazu BandoDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
Hiroshi SugiyamaDepartment of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.ORCID 0000-0001-8923-5946
Kyoto University · JP

Funding

Specific Recognition of G-quadruplexesR01CA236350 · NCI · KENT STATE UNIVERSITY · PI MAO, HANBIN · 2018 to 2022
$1.6M
NCI NIH HHS R01 CA236350
6 · The paper itself

Abstract

Telomeres are closely associated with cellular senescence and cancer. Although some techniques have been developed to label telomeres in living cells for study of telomere dynamics, few biocompatible near-infrared probes based on synthetic molecules have been reported. In this study, we developed a near-infrared fluorogenic pyrrole-imidazole polyamide probe (

Indexed as

Cell Line, TumorDNAFluorescent DyesHumansImidazolesIntercalating AgentsMitosisNylonsOptical ImagingPyrrolesRhodaminesSiliconSpectroscopy, Near-InfraredTelomereDNAFluorescent DyesImidazolesIntercalating AgentsNylonsPyrrolesRhodaminesSilicon

Identifiers

PMID32955878
PMCPMC7683039
OpenAlexW3087434963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.