ArticleJournal of human nutrition and dietetics : the official journal of the British Dietetic Association2021
Relationship between intake and plasma concentrations of vitamin B12 and folate in 873 adults with a physically active lifestyle: a cross-sectional study.
Article in Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 12 citations in OpenAlex.
- A Narrative Review of Candidate Biomarkers of Total Fruit and Vegetable Intake.Nutrition bulletin · 2026Review
- Association between serum folate and T cell subsets in a population-based study.European journal of nutrition · 2026Article
- Dietary and other lifestyle correlates of serum folate levels among female students at An-Najah National University in Palestine: a cross-sectional study.BMC nutrition · 2026Article
- Correlates of serum holo-Transcobalamin in the elderly general population.European journal of nutrition · 2025Article
- Article
- A Framework to Guide Defining an Upper Threshold of Crystalline Vitamin B12 in Foods and Food Supplements.Current nutrition reports · 2025Review
- Association of dietary intake with micronutrient deficiency in Indian school children: a cross-sectional study.Journal of nutritional science · 2023Article
- Relationship between high dose intake of vitamin B12 and glaucoma: Evidence from NHANES 2005-2008 among United States adults.Frontiers in nutrition · 2023Article
- Article
- Relationship between intake and plasma concentrations of vitamin B12 and folate in 873 adults with a physically active lifestyle: a cross-sectional study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2021Article
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin B12 and folate function as co-factors in pathways used during physical activity. Physical activity may therefore increase vitamin requirements, leading to a risk of deficient plasma concentrations. We aimed to investigate the relationship between intake and plasma concentrations of vitamin B12 and folate in physically active adults, as well as identify other determinants of vitamin B12 and folate plasma concentrations.
methodsThe study population consisted of 873 adults (528 men and 345 women), aged 19-78 years, who participated in a 4-day walking event. The relationship between intake and plasma concentrations of vitamin B12 and folate was assessed using correlation and linear regression analyses. In addition, potential other determinants (sex, age, body mass index, energy intake and physical activity) of vitamin plasma concentrations were investigated.
resultsSignificant positive correlations were observed between intake and plasma concentrations of vitamin B12 [Pearson's correlation coefficient = 0.15; 95% confidence interval (CI) = 0.08-0.21] and folate (Pearson's correlation coefficient = 0.18; 95% CI = 0.12-0.25). In addition to vitamin intake, sex, age and energy intake were also determinants of both vitamin B12 and folate plasma concentrations in multivariable regression models.
conclusionsThe results suggest a positive association between intake and plasma concentrations for both vitamin B12 and folate in physically active people. By contrast to our hypothesis, physical activity was not a determinant of vitamin B12 and folate plasma concentrations. However, sex, age and energy intake were found to be determinants. Thus, when studying the relationship between intake and plasma concentrations of vitamin B12 or folate, these factors should be taken into account.
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