Evidence map›Paper›PMID 32955737›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021

Galectin-Glycan Interactions: Guidelines for Monitoring by

Tammo Diercks, Francisco J Medrano, Forrest G FitzGerald, Donella Beckwith, Martin Jaeger Pedersen, Mark Reihill, Anna-Kristin Ludwig, Antonio Romero, Stefan Oscarson, Maré Cudic and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. What is the Sugar Code?Chembiochem : a European journal of chemical biology · 2022
    Review
  8. Article
  9. Pharmaceutics · 2022
    Article
  10. Article
  11. Galectin-Glycan Interactions: Guidelines for Monitoring byChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Tammo DiercksNMR Facility, CiC bioGUNE, Parque Tecnológico de Bizkaia, Ed. 800, 48160, Derio, Spain.ORCID http://orcid.org/0000-0002-5200-0905
Francisco J MedranoStructural and Chemical Biology, Centro de Investigaciones, Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040, Madrid, Spain.ORCID http://orcid.org/0000-0002-8185-9751
Forrest G FitzGeraldDepartment of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL, 33431, USA.
Donella BeckwithDepartment of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL, 33431, USA.ORCID http://orcid.org/0000-0002-2124-4931
Martin Jaeger PedersenCenter for Synthesis and Chemical Biology, University College Dublin, Belfield, Dublin, 4, Ireland.
Mark ReihillCenter for Synthesis and Chemical Biology, University College Dublin, Belfield, Dublin, 4, Ireland.
Anna-Kristin LudwigTierärztliche Fakultät, Institut für Physiologische Chemie, Ludwig-Maximilians-Universität München, Veterinärstr. 13, 80539, München, Germany.
Antonio RomeroStructural and Chemical Biology, Centro de Investigaciones, Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040, Madrid, Spain.ORCID http://orcid.org/0000-0002-6990-6973
Stefan OscarsonCenter for Synthesis and Chemical Biology, University College Dublin, Belfield, Dublin, 4, Ireland.ORCID http://orcid.org/0000-0002-8273-4918
Maré CudicDepartment of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL, 33431, USA.ORCID http://orcid.org/0000-0002-7657-0400
Hans-Joachim GabiusTierärztliche Fakultät, Institut für Physiologische Chemie, Ludwig-Maximilians-Universität München, Veterinärstr. 13, 80539, München, Germany.ORCID http://orcid.org/0000-0003-3467-3900
Florida Atlantic University · USUniversity College Dublin · IECentro de Investigaciones Biológicas Margarita Salas · ESLudwig-Maximilians-Universität München · DECIC bioGUNE · ES

Funding

Mechanistic insight into tumor-associated MUC1 glycopeptides binding to macrophage galactose-type lectinR15CA242351 · NCI · FLORIDA ATLANTIC UNIVERSITY · PI CUDIC, MARE · 2019 to 2024
$878k
Euskal Herriko Unibertsitatea BG2019Ministerio de Economía y Competitividad BFU2016-77835-RMinistero de Ciencia y Innovacion SEV-2016-0644NCI NIH HHS R15 CA242351NIH HHS CA242351Science Foundation of Ireland 13/IA/1959Science Foundation of Ireland 16/RC/3889
6 · The paper itself

Abstract

Functional pairing between cellular glycoconjugates and tissue lectins like galectins has wide (patho)physiological significance. Their study is facilitated by nonhydrolysable derivatives of the natural O-glycans, such as S- and Se-glycosides. The latter enable extensive analyses by specific

Indexed as

GalectinsNuclear Magnetic Resonance, BiomolecularPolysaccharidesBinding SitesDeuterium OxideHumansIsotopesLigandsProtein BindingSeleniumSolventsDeuterium OxideGalectinsIsotopesLigandsPolysaccharidesSeleniumSelenium-77Solvents77Se NMR spectroscopycalorimetrycircular dichroismgalectinsselenoglycosides

Identifiers

PMID32955737
PMCPMC7839768
OpenAlexW3087132815

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.