Evidence map›Paper›PMID 32955662›Full record

ArticleWorld journal of urology2021

Clinical outcome of robot-assisted residual mass resection in metastatic nonseminomatous germ cell tumor.

Joost M Blok, Henk G van der Poel, J Martijn Kerst, Axel Bex, Oscar R Brouwer, J L H Ruud Bosch, Simon Horenblas, Richard P Meijer

Open access · hybridAbstract read
In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Joost M BlokDepartment of Oncological Urology, University Medical Center Utrecht, Utrecht, The Netherlands. j.m.blok-3@umcutrecht.nl.ORCID http://orcid.org/0000-0002-9722-8487
Henk G van der PoelDepartment of Urology, The Netherlands Cancer Institute, Utrecht, The Netherlands.
J Martijn KerstDepartment of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Axel BexDepartment of Urology, The Netherlands Cancer Institute, Utrecht, The Netherlands.
Oscar R BrouwerDepartment of Urology, The Netherlands Cancer Institute, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0001-6244-0456
J L H Ruud Bosch *Department of Oncological Urology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0003-4833-0538
Simon HorenblasDepartment of Urology, The Netherlands Cancer Institute, Utrecht, The Netherlands.
Richard P MeijerDepartment of Oncological Urology, University Medical Center Utrecht, Utrecht, The Netherlands. rmeijer6@umcutrecht.nl.ORCID http://orcid.org/0000-0003-2510-7982
The Netherlands Cancer Institute · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the outcome of robot-assisted residual mass resection (RA-RMR) in nonseminomatous germ cell tumor (NSGCT) patients with residual tumor following chemotherapy. PATIENTS AND

methodsRetrospective medical chart analysis of all patients with NSGCT undergoing RA-RMR at two tertiary referral centers between January 2007 and April 2019. Patients were considered for RA-RMR in case of a residual tumor between 10 and 50 mm at cross-sectional computed tomography (CT) imaging located ventrally or laterally from the aorta or vena cava, with normalized tumor markers following completion of chemotherapy, and no history of retroperitoneal surgery.

resultsA total of 45 patients were included in the analysis. The Royal Marsden stage before chemotherapy was IIA in 13 (28.9%), IIB in 16 (35.6%), IIC in 3 (6.7%) and IV in 13 patients (28.9%). The median residual tumor size was 1.9 cm (interquartile range [IQR] 1.4-2.8; range 1.0-5.0). Five procedures (11.1%) were converted to an open procedure due to a vascular injury (n = 2), technical difficulty (n = 2) or tumor debris leakage (n = 1). A postoperative adverse event occurred in two patients (4.4%). Histopathology showed teratoma, necrosis and viable cancer in 29 (64.4%), 14 (31.1%), and two patients (4.4%), respectively. After a median follow-up of 41 months (IQR 22-70), one patient (2.2%) relapsed in the retroperitoneum. The one- and 2-year recurrence-free survival rate was 98%.

conclusionRA-RMR is an appropriate treatment option in selected patients, potentially providing excellent cure rates with minimal morbidity. Long-term outcome data are needed to further support this strategy and determine inclusion and exclusion criteria.

Indexed as

Robotic Surgical ProceduresAdultHumansMaleNeoplasm MetastasisNeoplasm, ResidualNeoplasms, Germ Cell and EmbryonalRetrospective StudiesTesticular NeoplasmsTreatment OutcomeUrologic Surgical Procedures, MaleYoung AdultNonseminomatous germ cell tumorRetroperitoneal lymph node dissectionRobot-assisted retroperitoneal lymph node dissectionRobotic surgeryTesticular cancerTesticular germ cell tumor

Identifiers

PMID32955662
PMCPMC8217018
OpenAlexW3087129429

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.