Evidence map›Paper›PMID 32955647›Full record

ArticleJournal, genetic engineering & biotechnology2020

Phyto-nano-hybrids of Ag-CuO particles for antibacterial activity against drug-resistant pathogens.

Syed Baker, Perianova Olga, Rukosueva Tatiana, Potkina Nadezhda, Garkusha Tatyana, Rukovets Tatyana, Elena Saveleva, Khokhlova Olga, Gudkova Elizaveta, Gildeeva Karina and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Journal, genetic engineering & biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Green synthesis of biocompatible FeScientific reports · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Syed BakerDepartment of Microbiology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022. syedbaker3@gmail.com.ORCID http://orcid.org/0000-0003-0554-8764
Perianova OlgaDepartment of Microbiology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Rukosueva TatianaDepartment of Microbiology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Potkina NadezhdaDepartment of Microbiology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Garkusha TatyanaKrasnoyarsk State Territorial Bureau of Pathology, Partizana Zheleznyaka str. 3 "D", Krasnoyarsk City, Russian Federation, 660022.
Rukovets TatyanaDepartment of Biochemistry, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, ul Partizana Zheleznyaka, 1, Krasnoyarsk, Russian Federation, 660021.
Elena SavelevaDepartment of Pharmaceutical technology and Pharmacognos, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Khokhlova OlgaDepartment of Microbiology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Gudkova ElizavetaDepartment of Microbiology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Gildeeva KarinaDepartment of Microbiology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Udegova EkaterinaDepartment of Microbiology, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Sergeenako AnastasiaDepartment of Pharmaceutical technology and Pharmacognos, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Putintseva MargaritaDepartment of Pharmaceutical technology and Pharmacognos, Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Partizana-Zheleznyaka street, 1, Krasnoyarsk, Siberia, Russian Federation, 660022.
Krasnoyarsk State Medical University · RUKrasnoyarsk Regional Clinical Hospital · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study reports the antibacterial potential of phyto-nano-hybrid particles Ag-CuO (silver-copper oxide) against drug-resistant pathogens isolated from a Russian hospital in Krasnoyarsk, Siberia. The synthesis of nano-hybrid was achieved by phytogenic source by using leaves of Murraya koenigii. The nano-hybrid particles were well characterized using hyphenated techniques and results of the antibacterial assay was tabulated.

resultsThe UV-visible spectra displayed absorption at 420 nm with the shoulder peak at 355 nm indicating the hybridization. The FTIR analysis revealed the presence of phenol, amine, methyl, carbohydrate and aromatic as major functional groups. The XRD analysis revealed the presence of Bragg's intensities at 2 theta angle depicting the crystalline nature of Ag-CuO nano-hybrid. The TEM analysis displayed the polydispered properties of Ag-CuO nano-hybrid with the size in the range of 60-80 nm exhibiting different shapes ranging from spherical, rod and oval. The antibacterial activity of Ag-CuO nano-hybrid was tested against multidrug-resistant pathogens that resulted in highest activity against P. aeruginosa strain with an inhibition zone of 14 mm in diameter. The MIC concentrations ranged from 0.3125 to 2.5 μg/ml and broth dilution assay displayed dose-dependent properties of Ag-CuO nano-hybrid particles.

conclusionThe obtained results are interesting to report the preliminary insight to develop biocompatible hybrid particles to combat drug-resistant pathogens. The developed nano-hybrid particles displayed activity against all the test pathogens investigated against both Gram-positive and Gram-negative bacteria. Thus, the study forms preliminary investigation to report nano-hybrid particles as broad spectrum antibacterial agents.

Indexed as

Antibacterial propertiesCopper oxide nanoparticlesMulti-drug resistanceNano-hybridPhytogenicSilver nanoparticles

Identifiers

PMID32955647
PMCPMC7505910
OpenAlexW3087057578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.