Evidence map›Paper›PMID 32955442›Full record

ArticleJMIR mHealth and uHealth2020

Supervised Digital Neuropsychological Tests for Cognitive Decline in Older Adults: Usability and Clinical Validity Study.

Francesca Lunardini, Matteo Luperto, Marta Romeo, Nicola Basilico, Katia Daniele, Domenico Azzolino, Sarah Damanti, Carlo Abbate, Daniela Mari, Matteo Cesari and 2 more

Open access · goldAbstract read
In one paragraph

Article in JMIR mHealth and uHealth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. The Role of Clinical Assessment in the Era of Biomarkers.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Francesca Lunardini *Nearlab, Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy.ORCID 0000-0003-4705-6733
Matteo Luperto *AISLab, Department of Computer Science, University of Milano, Milano, Italy.ORCID 0000-0002-8976-2073
Marta RomeoSchool of Computer Science, The University of Manchester, Manchester, United Kingdom.ORCID 0000-0003-4438-0255
Nicola BasilicoAISLab, Department of Computer Science, University of Milano, Milano, Italy.ORCID 0000-0002-4512-3480
Katia DanieleGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.ORCID 0000-0003-1404-658X
Domenico AzzolinoGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.ORCID 0000-0002-4910-7373
Sarah DamantiGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.ORCID 0000-0002-2399-3688
Carlo AbbateGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.ORCID 0000-0002-0368-3834
Daniela MariGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.ORCID 0000-0002-6950-0789
Matteo CesariGeriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.ORCID 0000-0002-0348-3664
Nunzio Alberto BorgheseAISLab, Department of Computer Science, University of Milano, Milano, Italy.ORCID 0000-0002-0925-3448
Simona FerranteNearlab, Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy.ORCID 0000-0002-7835-1965
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITPolitecnico di Milano · ITUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDementia is a major and growing health problem, and early diagnosis is key to its management.

objectiveWith the ultimate goal of providing a monitoring tool that could be used to support the screening for cognitive decline, this study aims to develop a supervised, digitized version of 2 neuropsychological tests: Trail Making Test and Bells Test. The system consists of a web app that implements a tablet-based version of the tests and consists of an innovative vocal assistant that acts as the virtual supervisor for the execution of the test. A replay functionality is added to allow inspection of the user's performance after test completion.

methodsTo deploy the system in a nonsupervised environment, extensive functional testing of the platform was conducted, together with a validation of the tablet-based tests. Such validation had the two-fold aim of evaluating system usability and acceptance and investigating the concurrent validity of computerized assessment compared with the corresponding paper-and-pencil counterparts.

resultsThe results obtained from 83 older adults showed high system acceptance, despite the patients' low familiarity with technology. The system software was successfully validated. A concurrent validation of the system reported good ability of the digitized tests to retain the same predictive power of the corresponding paper-based tests.

conclusionsAltogether, the positive results pave the way for the deployment of the system to a nonsupervised environment, thus representing a potential efficacious and ecological solution to support clinicians in the identification of early signs of cognitive decline.

Indexed as

Cognitive DysfunctionAgedAged, 80 and overEarly DiagnosisFemaleHumansMaleNeuropsychological TestsSoftwareTechnologyagingBells Testcomputerized testingdementiaearly diagnosiseHealthmild cognitive impairmentneuropsychological assessmentTrail Making Test

Identifiers

PMID32955442
PMCPMC7536607
OpenAlexW3087527309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.