Evidence map›Paper›PMID 32955439›Full record

ArticleeLife2020

Kristoffer B Hansen, Christian Staehr, Palle D Rohde, Casper Homilius, Sukhan Kim, Mette Nyegaard, Vladimir V Matchkov, Ebbe Boedtkjer

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Guidelines for evaluating endothelial function in vascular tissue.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. The solution to bicarbonate.American journal of physiology. Heart and circulatory physiology · 2022
    Article
  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Kristoffer B HansenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Christian StaehrDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Palle D RohdeDepartment of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark.ORCID 0000-0003-4347-8656
Casper HomiliusDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Sukhan KimDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Mette NyegaardDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Vladimir V MatchkovDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-3303-1095
Ebbe BoedtkjerDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-5078-9279
Aarhus University · DKFlinders Medical Centre · AU

Funding

Det Frie Forskningsråd 4183-00258BDet Frie Forskningsråd 7025-00050ALundbeckfonden R287-2018-735Lundbeckfonden R93-A8859
6 · The paper itself

Abstract

Acid-base conditions modify artery tone and tissue perfusion but the involved vascular-sensing mechanisms and disease consequences remain unclear. We experimentally investigated transgenic mice and performed genetic studies in a UK-based human cohort. We show that endothelial cells express the putative HCO

Indexed as

AnimalsBicarbonatesBiological Specimen BanksEndothelial CellsHumansIschemiaMaleMiceMice, KnockoutReceptor-Like Protein Tyrosine Phosphatases, Class 5United KingdomVasodilationBicarbonatesPTPRG protein, humanPtprg protein, mouseReceptor-Like Protein Tyrosine Phosphatases, Class 5acidosisbicarbonatecerebral blood flow and metabolismendothelium-dependent vasorelaxationgeneticsgenomicshumanischemiamedicinemetabolic regulationmouse

Identifiers

PMID32955439
PMCPMC7541084
OpenAlexW3087129906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.