Evidence map›Paper›PMID 32955429›Full record

ArticleParasite (Paris, France)2020

Seroprevalence of Toxoplasma gondii among healthy blood donors in two locations in Tunisia and associated risk factors.

Arwa Lachkhem, Ibtissem Lahmar, Lokman Galal, Oussama Babba, Habib Mezhoud, Mohssen Hassine, Ahmed Lachkhem, Marie-Laure Dardé, Aurélien Mercier, Hamouda Babba

Abstract read
In one paragraph

Article in Parasite (Paris, France), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Microorganisms · 2026
    Article
  3. Article
  4. Serological, Molecular, and Epidemiological Investigation ofTropical medicine and infectious disease · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Heliyon · 2024
    Review
  12. The Medical Relevance ofMicroorganisms · 2023
    Review
  13. Article
  14. Review
  15. Assessment of seroprevalence ofIranian journal of microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arwa LachkhemLaboratoire de Parasitologie-Mycologie Médicale et Moléculaire, Département de Biologie Clinique B, Faculté de Pharmacie de Monastir, Université de Monastir, 5000 Monastir, Tunisia.
Ibtissem LahmarLaboratoire de Parasitologie-Mycologie Médicale et Moléculaire, Département de Biologie Clinique B, Faculté de Pharmacie de Monastir, Université de Monastir, 5000 Monastir, Tunisia.
Lokman GalalINSERM, Université Limoges, CHU Limoges, IRD, U1094 Neuroépidémiologie Tropicale, Institut d'Epidémiologie et de Neurologie Tropicale, GEIST, 87000 Limoges, France.
Oussama BabbaLaboratoire de Parasitologie-Mycologie Médicale et Moléculaire, Département de Biologie Clinique B, Faculté de Pharmacie de Monastir, Université de Monastir, 5000 Monastir, Tunisia - Centre de Maternité et de Néonatologie de Monastir, 5000 Monastir, Tunisia.
Habib MezhoudLaboratoire de Parasitologie-Mycologie Médicale et Moléculaire, Département de Biologie Clinique B, Faculté de Pharmacie de Monastir, Université de Monastir, 5000 Monastir, Tunisia.
Mohssen HassineHématologie - Banque du Sang de Monastir, 5000 Monastir, Tunisia.
Ahmed LachkhemCentre de Transfusion Sanguine de Gafsa, 2100 Gafsa, Tunisia.
Marie-Laure DardéINSERM, Université Limoges, CHU Limoges, IRD, U1094 Neuroépidémiologie Tropicale, Institut d'Epidémiologie et de Neurologie Tropicale, GEIST, 87000 Limoges, France - Centre National de Référence (CNR) Toxoplasmose/Toxoplasma Biological Center (BRC), Centre Hospitalier-Universitaire Dupuytren, 87000 Limoges, France.
Aurélien MercierINSERM, Université Limoges, CHU Limoges, IRD, U1094 Neuroépidémiologie Tropicale, Institut d'Epidémiologie et de Neurologie Tropicale, GEIST, 87000 Limoges, France - Centre National de Référence (CNR) Toxoplasmose/Toxoplasma Biological Center (BRC), Centre Hospitalier-Universitaire Dupuytren, 87000 Limoges, France.
Hamouda BabbaLaboratoire de Parasitologie-Mycologie Médicale et Moléculaire, Département de Biologie Clinique B, Faculté de Pharmacie de Monastir, Université de Monastir, 5000 Monastir, Tunisia - Centre de Maternité et de Néonatologie de Monastir, 5000 Monastir, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasma gondii is a protozoan parasite that can be transmitted to humans through a variety of routes including blood transfusion. This study aimed to investigate the seroprevalence of T. gondii infection and associated risk factors in healthy blood donors in Tunisia. A total of 800 healthy blood donors from two blood centers in south and coastal Tunisia were analyzed for anti-T. gondii IgG and IgM antibodies by indirect immunofluorescence assay (IFA) and enzyme-linked immunoassays (ELISA), respectively. Structured questionnaires were used to gather information on risk factors for T. gondii infection during collection. The overall seroprevalence was 44.4% of which 352 (44%) and 3 (0.4%) were positive for IgG and both IgG and IgM anti-T. gondii antibodies, respectively. Multivariate analysis showed that T. gondii seropositivity was significantly associated with the birth place (adjusted odds ratio [OR] = 2.72; 95% confidence interval [CI]: 1.49-4.94) and the age of the donors (adjusted OR = 4.98; 95% CI: 1.50-16.58) which are independent risk factors. In addition, the variables of hand washing before eating (adjusted OR = 0.52; 95% CI: 0.37-0.74) and living in an urban environment (adjusted OR = 0.30; 95% CI: 0.13-0.71) are two protective factors. This study provided the first data on the seroprevalence and epidemiology of T. gondii infection in healthy blood donors in Tunisia.

Indexed as

Seroepidemiologic StudiesToxoplasmosisAnimalsAntibodies, ProtozoanBlood DonorsCatsCross-Sectional StudiesFemaleHumansImmunoglobulin GImmunoglobulin MRisk FactorsToxoplasmaTunisiaAntibodies, ProtozoanImmunoglobulin GImmunoglobulin MBlood donorsRisk factorsSeroprevalenceToxoplasma gondiiTunisia

Identifiers

PMID32955429
PMCPMC7504876

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.