SynthesisClinical and translational gastroenterology2020
Esophageal Pathophysiologic Changes and Adenocarcinoma After Bariatric Surgery: A Systematic Review and Meta-Analysis.
Synthesis in Clinical and translational gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Treatment of Barrett's esophagus following sleeve gastrectomy by conversion to Roux-en-Y gastric bypass: a systematic review and pooled proportions analysis.Surgical endoscopy · 2026Pooled it
- Gastro-esophageal diagnostic workup before bariatric surgery or endoscopic treatment for obesity: position statement of the International Society of Diseases of the Esophagus.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Guideline
- Barrett's Esophagus in Obese Patient Post-Roux-en-Y Gastric Bypass: a Systematic Review.Obesity surgery · 2022Pooled it
- Bariatric metabolic surgery and cancer risk: Target trial emulation using iterative time distribution matching.Biomolecules & biomedicine · 2025Article
- Laparoscopic Upper Polar Esophagogastrectomy with Gastroplasty Using Gastric Remnant After Roux-en-Y Gastric Bypass for Recurrent Gastroesophageal Junction Adenocarcinoma.Obesity surgery · 2025Article
- Endoscopic Management of Postsurgical Complications after Metabolic and Bariatric Surgery.Visceral medicine · 2025Review
- Effect of sleeve gastrectomy on distal esophagus at 5 and 10 years.Surgical endoscopy · 2025Article
- Gastroesophageal reflux disease and the phantom of Barrett's esophagus after most-often-used bariatric procedures: are future investigations necessary?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025Review
- Varying concentrations of tyrosine kinase inhibitors in chronic myeloid leukemia patients following bariatric surgery: a case series.Annals of hematology · 2024Article
- Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.Cancer chemotherapy and pharmacology · 2024Article
- Post-bariatric Surgery Changes in Secondary Esophageal Motility and Distensibility Parameters.Obesity surgery · 2024Article
- Impact of Bariatric Surgery in the Short and Long Term: A Need for Time-Dependent Dosing of Drugs.Obesity surgery · 2023Review
- Mixed Esophageal Disease (MED): A New Concept.Digestive diseases and sciences · 2023Review
- Sleeve gastrectomy morphology and long-term weight-loss and gastroesophageal reflux disease outcomes.Surgical endoscopy · 2023Article
- The Novel Conduit: Challenges of Esophagectomy After Bariatric Surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Turnkey algorithmic approach for the evaluation of gastroesophageal reflux disease after bariatric surgery.Gastroenterology report · 2023Review
- Feasibility and Efficacy of Magnetic Sphincter Augmentation for the Management of Gastroesophageal Reflux Disease Post-Sleeve Gastrectomy for Obesity.Obesity surgery · 2023Observational
- Oesophageal and Gastric Cancer After Bariatric Surgery: an Up-to-Date Systematic Scoping Review of Literature of 324 Cases.Obesity surgery · 2022Article
- Stomatognathic System Changes in Obese Patients Undergoing Bariatric Surgery: A Systematic Review.Journal of personalized medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo assess the effects of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) on acid reflux and esophageal motor function and to evaluate the observation of esophageal adenocarcinoma (EAC) after bariatric surgery.
methodsWe searched 5 databases for adults who underwent SG or RYGB and had esophageal pH test and/or esophageal manometry before and after surgery. A separate systemic search of observational studies and a retrospective review at 3 institutions of adults who developed EAC after these surgeries were conducted. Outcomes were changes in manometric and pH parameters and EAC cases after SG and RYGB.
resultsA total of 27 nonrandomized studies (SG: 612 patients; RYGB: 470 patients) were included. After SG, lower esophageal sphincter pressure and esophageal body amplitude were decreased and the risk of ineffective esophageal motility was increased. Total and recumbent acid exposure times were increased. After RYGB, an increased risk of ineffective esophageal motility was observed. Total, upright, and recumbent acid exposure times were decreased. The total reflux episodes remained unchanged but with increased nonacid reflux and decreased acid reflux events. Including our largest series, 31 EAC cases have been reported to date after SG and RYGB. DISCUSSION: This systematic review demonstrates increased acid reflux after SG and decreased acid reflux after RYGB. An observed increased nonacid reflux after RYGB might contribute to failure of gastroesophageal reflux disease improvement. This refluxate might be noxious to the esophagus, warranting further studies. RYGB might not entirely preserve esophageal function as previously believed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.