ArticleClinical and translational gastroenterology2020
Collagenous Gastritis in Children: Incidence, Disease Course, and Associations With Autoimmunity and Inflammatory Markers.
Article in Clinical and translational gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Approach to anaemia in gastrointestinal disease: A position paper by the ESPGHAN Gastroenterology Committee.Journal of pediatric gastroenterology and nutrition · 2025Guideline
- Pediatric Eosinophil-Predominant Collagenous Gastritis: From Conventional Therapy to Dupilumab: A Case Report.Reports (MDPI) · 2026Article
- [Clinical analysis of 4 cases of pediatric collagenous gastritis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Rare Concurrent Findings With Collagenous Gastroduodenitis in a Pediatric Patient.ACG case reports journal · 2026Article
- Diagnostic Approach to Pediatric Collagenous Gastritis Based on a Case Series and Literature Review.Pediatric gastroenterology, hepatology & nutrition · 2026Article
- Collagenous gastritis: A cause of anemia and gastric nodularity in the pediatric population.JPGN reports · 2026Article
- The Plot Thickens - Is Eosinophilic Gastritis Related to Collagenous Gastritis?Digestive diseases and sciences · 2026Article
- Article
- Paediatric Collagenous Gastritis with Transient Response to Steroid Therapy.European journal of case reports in internal medicine · 2026Article
- Case Report: Collagenous gastritis presenting with refractory dyspepsia and diffuse gastric atrophic-appearing changes.Frontiers in medicine · 2026Article
- Collagenous gastritis: current understanding of a rare immune-mediated gastropathy across pediatric and adult phenotypes-from pathogenesis to therapeutic strategies.Frontiers in cell and developmental biology · 2026Review
- Collagenous gastritis: clinical features, histologic correlates and unanswered questions.Histopathology · 2025Review
- The plot thickens: A pediatric cases series on collagenous gastritis.JPGN reports · 2025Article
- Collagenous Gastritis: A Rare Cause of Hemorrhagic Shock.ACG case reports journal · 2025Article
- Co-occurrence of collagenous gastrointestinal disease in siblings in early childhood: New insight into a rare condition.JPGN reports · 2024Article
- Management of collagenous gastritis in children: Case series and literature review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Review
- Article
- Literature Review and a Relevant Case of Pediatric Collagenous Gastritis: A Rare but Important Etiology of Iron-Deficiency Anemia.JPGN reports · 2023Article
- Clinical and Pathologic Response to Vedolizumab in a Young Female Patient With Collagenous Gastritis.ACG case reports journal · 2023Article
- Collagenous Gastritis Is an Underdiagnosed Cause of Anemia and Abdominal Pain: Systematic Scoping Review.Digestive diseases and sciences · 2023Article
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Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCollagenous gastritis (CG), a rare disorder of unknown etiology, has been postulated to have immune-mediated mechanisms. We investigated (i) the incidence and prevalence of CG in a pediatric population; (ii) the clinical, endoscopic, and histologic characteristics of childhood-onset CG; and (iii) the evidence for autoimmunity and/or inflammatory activity in these patients.
methodsClinical, endoscopic, and histologic data were reviewed longitudinally in a population-based Swedish cohort of 15 patients with childhood-onset CG diagnosed in the period 2008-2019. A set of 11 autoantibodies, 4 blood inflammatory biomarkers, and the human leukocyte antigen DQ2/DQ8 genotype was analyzed cross-sectionally.
resultsThe incidence rate of childhood-onset CG was 0.25/100,000 person-years, with an incidence rate ratio of girls to boys of 4.2 (95% confidence interval, 1.2-15). The prevalence of CG was 2.1/100,000 in children aged younger than 18 years. The endoscopic and histologic findings remained pathologic in all the examined patients during a median follow-up of 4.4 years. Many patients had heredity for autoimmune disorders (47%) and/or tested positive for autoantibodies (40%) or human leukocyte antigen DQ2/DQ8 (53%). No associated autoimmune comorbidities were observed. The serum levels of calprotectin and amyloid A were increased in 10/15 (67%) and 5/15 (33%) of the patients, respectively, whereas plasma C-reactive protein levels were normal in all, but 1 patient. DISCUSSION: The results indicate that childhood-onset CG is rare and has a chronic disease course. Although signs of autoimmune predisposition are frequent, early development of autoimmune comorbidities seems seldom. Serum calprotectin and amyloid A represent novel candidate biomarkers of inflammatory activity in CG (see Visual Abstract, Supplementary Digital Content 4, http://links.lww.com/CTG/A349).
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