ArticleJournal of the Pediatric Infectious Diseases Society2021
Suppurative Intracranial Complications of Pediatric Sinusitis: A Single-Center Experience.
Article in Journal of the Pediatric Infectious Diseases Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Treatment of sinusitis in children: an Italian intersociety consensus (SIPPS-SIP-SITIP-FIMP-SIAIP-SIMRI-SIM-FIMMG).Italian journal of pediatrics · 2025Pooled it
- Sinogenic Subdural Empyema in an Adolescent: Multifocal Disease, Decompressive Craniotomy, and Complete Recovery.Cureus · 2026Article
- Intracranial Complications Following Acute Rhinosinusitis in a Pediatric Patient Requiring Surgery: A Case Report.Cureus · 2026Article
- Neurosurgical perspective on Pott's puffy tumor management of both adult and pediatric patients in Tasmania, Australia: illustrative cases.Journal of neurosurgery. Case lessons · 2025Article
- Cerebral Sinovenous Thrombosis in Children With Acute Bacterial Intracranial Infection.Neurology · 2025Observational
- Bilateral Frontal Sinus and Epidural Mucopyocele Drainage Using "Modified" Draf III.Case reports in otolaryngology · 2025Article
- Evaluation of the antimicrobial management of intracranial suppurative infections in a single pediatric institution.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Status Epilepticus with Fever in a Toddler with Pyogenic Meningitis Due to Complicated Acute Sphenoid Sinusitis.Journal of pediatrics. Clinical practice · 2024Article
- A Case Report of Frontal Sinus Abscess Complicated by Epidural Abscess with a Literature Review.Infection and drug resistance · 2024Article
- Pediatric Intracranial Abscess From Sinusitis Leading to Status Epilepticus: A Clinical Case Report.Cureus · 2024Article
- Article
- COVID-19 Co-Infection May Promote Development of Sinusitis Complication in Children.Children (Basel, Switzerland) · 2022Article
- Sequential Intravenous-Oral Therapy for PediatricOpen forum infectious diseases · 2022Article
- Management Strategy of Intracranial Complications of Sinusitis: Our Experience and Review of the Literature.Allergy & rhinology (Providence, R.I.)Review
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSuppurative intracranial complications of sinusitis are rare events in children and can lead to harmful neurologic sequelae and significant morbidity. We sought to review the presentation and management of patients admitted at our hospital with these conditions.
methodsThis was a retrospective study of pediatric patients admitted to a quaternary children's hospital from 2007 to 2019 for operative management of sinusitis with intracranial extension. Clinical characteristics, including surgical and microbiological data, were collected and analyzed.
resultsFifty-four patients were included; the median age was 11.0 years, and there was a male predominance. Eighty-nine percent of patients had prior healthcare visits for the current episode of sinusitis; 46% of patients had an abnormal neurologic exam on admission. Epidural abscess and subdural empyema were the most common complications, and subdural empyema was associated with repeat surgical intervention. The dominant pathogens were Streptococcus anginosus group organisms (74%). The majority of patients completed treatment parenterally, with a median duration of therapy of 35 days. Neurological sequelae, including epilepsy or ongoing focal deficits, occurred in 22% of patients. History of seizure or an abnormal neurological exam at admission were associated with neurological sequelae.
conclusionsClinicians should consider intracranial complications of sinusitis in patients with symptoms of sinusitis for >1 week. Patients should undergo urgent neuroimaging, as neurosurgical intervention is essential for these patients. Subdural empyema was associated with repeat neurosurgical intervention. Neurological sequelae occurred in 22% of patients, and new onset seizure or an abnormal neurological exam at admission were associated with neurological sequelae.
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