ArticleThe Journal of international medical research2020
Coronary flow reserve and microcirculatory resistance in patients with coronary tortuosity and without atherosclerosis.
Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- The impact of stenting on hemodynamic environment of tortuous coronary artery: results derived from a numerical simulation model.Frontiers in bioengineering and biotechnology · 2026Article
- Effect of coronary tortuosity on invasive physiology.BMJ case reports · 2022Article
- Index of microcirculatory resistance: state-of-the-art and potential applications in computational simulation of coronary artery disease.Journal of Zhejiang University. Science. B · 2022Article
- Fractional Flow Reserve: Patient Selection and Perspectives.Vascular health and risk management · 2021Review
- Relation Between Coronary Tortuosity and Vasomotor Dysfunction in Patients Without Obstructed Coronaries?Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCoronary tortuosity may affect epicardial coronary arterial blood flow. This study aimed to investigate the effect of coronary tortuosity on coronary flow reserve and the coronary microcirculation in patients without apparent coronary atherosclerosis.
methodsProspective patients (n = 8, 3 men, mean age: 58 ± 6.0 years) with coronary tortuosity and without apparent coronary atherosclerosis were enrolled. Coronary tortuosity was defined by the finding of ≥three bends (defined as a ≥45° change in vessel direction) along the main trunk of the left anterior descending artery or left circumflex artery. Coronary flow reserve and the index of microcirculatory resistance were measured by the thermodilution technique.
resultsA total of eight coronary arteries with coronary tortuosity were analyzed. The mean fractional flow reserve was 0.98 ± 0.007. The mean coronary flow reserve was 1.5 ± 0.3, which is much lower than that in the normal coronary artery as reported in the literature. The mean index of microcirculatory resistance was 26.7 ± 2.3, which is much higher than that in the normal coronary artery.
conclusionsCoronary tortuosity is associated with decreased coronary flow reserve and an increased index of microcirculatory resistance.
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