Evidence map›Paper›PMID 32954902›Full record

ReviewJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Benefits of exercise training on cerebrovascular and cognitive function in ageing.

Edward S Bliss, Rachel Hx Wong, Peter Rc Howe, Dean E Mills

3 registry-linked trialsOpen access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 111 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 7 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05937009 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Orientation Exercise Program on Older Adults, Motor Skills, Cognitive and Emotional State: a Pilot Study

TypeinterventionalSponsorUniversity of ÉvoraRan2023 to 2024Enrolled54ConditionsCommunity-dwelling Older AdultsArmsOrienteering exercise program
NCT06293846 nacompletednot on this mapstarted 2024, after this paper: background citation

BeFit Toolbox Collaboration: Building Empowerment Through Fitness

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2024 to 2025Enrolled46ConditionsLow-Income Population, Women's HealthArmsWhat I Learned at Home
NCT07324330 narecruitingnot on this mapstarted 2025, after this paper: background citation

Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity

TypeinterventionalSponsorUniversity Hospital, BonnRan2025 to 2029Enrolled130ConditionsParkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Basal Ganglia DiseasesArmsIncrease of physical activity volume and intensity with the use of a motivational smartphone application
3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 7 syntheses or guidelines pooled it, 174 citations in OpenAlex.

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  15. One-year aerobic exercise increases cerebral blood flow in cognitively normal older adults.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Edward S BlissRespiratory and Exercise Physiology Research Group, School of Health and Wellbeing, University of Southern Queensland, Ipswich, Queensland, Australia.
Rachel Hx WongCentre for Health, Informatics, and Economic Research, Institute for Resilient Regions, University of Southern Queensland, Ipswich, Queensland, Australia.
Peter Rc HoweCentre for Health, Informatics, and Economic Research, Institute for Resilient Regions, University of Southern Queensland, Ipswich, Queensland, Australia.
Dean E MillsRespiratory and Exercise Physiology Research Group, School of Health and Wellbeing, University of Southern Queensland, Ipswich, Queensland, Australia.
University of Southern Queensland · AUUniversity of Newcastle Australia · AUUniversity of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Derangements in cerebrovascular structure and function can impair cognitive performance throughout ageing and in cardiometabolic disease states, thus increasing dementia risk. Modifiable lifestyle factors that cause a decline in cardiometabolic health, such as physical inactivity, exacerbate these changes beyond those that are associated with normal ageing. The purpose of this review was to examine cerebrovascular, cognitive and neuroanatomical adaptations to ageing and the potential benefits of exercise training on these outcomes in adults 50 years or older. We systematically searched for cross-sectional or intervention studies that included exercise (aerobic, resistance or multimodal) and its effect on cerebrovascular function, cognition and neuroanatomical adaptations in this age demographic. The included studies were tabulated and described narratively. Aerobic exercise training was the predominant focus of the studies identified; there were limited studies exploring the effects of resistance exercise training and multimodal training on cerebrovascular function and cognition. Collectively, the evidence indicated that exercise can improve cerebrovascular function, cognition and neuroplasticity through areas of the brain associated with executive function and memory in adults 50 years or older, irrespective of their health status. However, more research is required to ascertain the mechanisms of action.

Indexed as

AgingExerciseAnimalsBrainCognitionCross-Sectional StudiesHealth StatusHumansOxygen ConsumptionResistance Trainingageingcerebrovascular functioncognitionDementiaexercise training

Identifiers

PMID32954902
PMCPMC7907999
OpenAlexW3087052420

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.