Evidence map›Paper›PMID 32954602›Full record

ReviewReviews in medical virology2021

Transplantation in the era of the Covid-19 pandemic: How should transplant patients and programs be handled?

Mohamed M NasrAllah, Noha A Osman, Mahmoud Elalfy, Paolo Malvezzi, Lionel Rostaing

Open access · bronzeAbstract readReview
In one paragraph

Review in Reviews in medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Observational
  3. Observational
  4. Article
  5. Review
  6. Review
  7. COVID-19 and Indirect Liver Injury: A Narrative Synthesis of the Evidence.Journal of clinical and translational hepatology · 2021
    Review
  8. Article
  9. Review
  10. Early detection of SARS-CoV-2 and other infections in solid organ transplant recipients and household members using wearable devices.Transplant international : official journal of the European Society for Organ Transplantation · 2021
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mohamed M NasrAllahDepartment of Nephrology, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt.ORCID https://orcid.org/0000-0001-5650-3000
Noha A OsmanDepartment of Nephrology, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt.
Mahmoud ElalfyMisr International Hospital, Cairo, Egypt.
Paolo MalvezziService de Néphrologie, Hémodialyse, Aphérèseset Transplantation Rénale, CHU Grenoble-Alpes, Grenoble, France.
Lionel RostaingService de Néphrologie, Hémodialyse, Aphérèseset Transplantation Rénale, CHU Grenoble-Alpes, Grenoble, France.ORCID https://orcid.org/0000-0002-5130-7286
Cairo University · EGCentre Hospitalier Universitaire de Grenoble · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the Covid-19 pandemic caused by SARS-CoV-2, transplant programs worldwide have been severely impacted with dwindling numbers of transplantations performed and a complete halt in several areas. In this review we examine whether SARS-CoV-2 infection presents differently in transplant recipients, whom and how we should test, how susceptible the transplant population is to overt infection and describe the range of outcomes. From retrieved published reports on SARS-CoV-2infections in 389solid organ transplant recipients reported in the literature, the overall mortality rate was 16.7% (n = 65); however for those with mild or moderate Covid-19 disease this was 2.9% and 2.3% respectively; conversely, for those with severe infection the mortality rate was 52.2%.We then address questions regarding halting transplantation programs during this pandemic, whether all human tissues being considered for transplantation are capable of transmitting the infection, and if we should alter immunosuppressive medications during the pandemic.

Indexed as

Transplant RecipientsCOVID-19COVID-19 TestingHumansOrgan TransplantationSARS-CoV-2Treatment OutcomeCovid-19immunosuppressionkidney transplantationmortalityoutcomesSARS-CoV-2solid organ transplantationwaiting list

Identifiers

PMID32954602
PMCPMC7537021
OpenAlexW3087175969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.