ArticleSleep2021
Sleep quality and risk of cancer: findings from the English longitudinal study of aging.
Article in Sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Sleep Traits to the Risk of Breast Cancer Disease Incidence, Adverse Progression and Mortality: Evidence From a Global Systematic Review and Meta-Analysis.International journal of public health · 2025Pooled it
- Higher Daytime Light Exposure Predicts Lower Risk of Gastrointestinal Cancer Incidence and Mortality.International journal of cancer · 2026Article
- Characterizing sleep-related complaints in head and neck cancer survivors with tumors of airway relevance following radiotherapy.Clinical and translational radiation oncology · 2026Article
- Can Disruption of Circadian Rhythms Be Linked to Radiation-Induced Acute Myeloid Leukaemia?Cancers · 2026Review
- Cardiovascular health assessed by life's essential 8 in Israeli adults aged ≥65 years and its association with long-term cancer incidence.Frontiers in aging · 2026Article
- Magnesium and Zinc Are Associated with Sleep Quality in Saudi Adults: Evidence from a Cross-Sectional Study.Nutrients · 2025Article
- Association Between Self-Reported Sleep Quality and Conversion From Mild Cognitive Impairment to Dementia: A Retrospective Cohort Study Using the English Longitudinal Study of Ageing.Brain and behavior · 2025Article
- Sleep disorders in patients with differentiated thyroid cancer: a case-control study.Endocrine · 2025Article
- A Randomized Controlled Trial of an Enhanced Version of a Cognitive-Behavioral Video Game Intervention Aimed at Promoting Active Aging: Assessments of Perceived Health and Healthy Lifestyle Habits at Pre- and Post-Intervention.Journal of clinical medicine · 2025Article
- Sleep health among sexual and gender minority people in the United States: A scoping review.Sleep medicine · 2025Article
- A Multimodal Sleep Foundation Model Developed with 500K Hours of Sleep Recordings for Disease Predictions.medRxiv : the preprint server for health sciences · 2025Article
- Sleep and Oxidative Stress: Current Perspectives on the Role of NRF2.Cellular and molecular neurobiology · 2024Review
- Sleep and liver function biomarkers in relation to risk of incident liver cancer: a nationwide prospective cohort study.BMC medicine · 2024Article
- Sleep fragmentation induces heart failure in a hypertrophic cardiomyopathy mouse model by altering redox metabolism.iScience · 2024Article
- Sleep Pattern, Lifestyle Pattern, and Risks of Overall and 20 Types of Cancers: Findings From the UK Biobank Cohort.International journal of public health · 2024Article
- Poor Sleep Quality and Its Influencing Factors Among Iranian Patients with Esophageal and Gastric Cancer.Middle East journal of digestive diseases · 2024Article
- Development and validation of a nomogram for predicting the risk of developing gastric cancer based on a questionnaire: a cross-sectional study.Frontiers in oncology · 2024Article
- Fatigue and fallibility: the perils of prolonged shifts for neonatologists.Journal of perinatology : official journal of the California Perinatal Association · 2023Review
- Dietary insulinemic potential, sleep quality and quantity in Iranian adults: Yazd health study and TAMYZ study.BMC nutrition · 2023Article
- Tackling Insomnia Symptoms through Vestibular Stimulation in Patients with Breast Cancer: A Perspective Paper.Cancers · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectiveTo prospectively examine the association between sleep quality and incident cancer risk in the elderly.
methodsA total of 10,036 participants aged ≥50 years free of cancer at baseline from the English Longitudinal Study of Ageing at wave 4 (2008) were included, and followed up until 2016. The primary endpoint was new onset physician-diagnosed cancer. Sleep quality was assessed by four questions regarding the frequency of sleep problems and overall subjective feeling of sleep quality in the last month, with higher score denoting poorer sleep quality. The multivariable Cox regression model was used to calculate hazard ratio (HR) with 95% confidence interval (CI) for incident cancer risk according to sleep quality.
resultsAt 8-year follow-up, a total of 745 (7.4%) participants developed cancer. Compared with good sleep quality at baseline, HR (95% CI) for incident cancer risk was 1.328 (1.061, 1.662) for intermediate quality, 1.586 (1.149, 2.189) for poor quality. Similarly, compared with maintaining good sleep quality in the first 4 years, HR (95% CI) for incident cancer risk was 1.615 (1.208, 2.160) for maintaining intermediate quality and 1.608 (1.043, 2.480) for maintaining poor quality. The exclusion of participants with family history of cancer or abnormal sleep duration yielded consistent results.
conclusionsPoor sleep quality is positively associated with the long-term risk of developing cancer in an elderly cohort. Both medical staffs and the general public should pay more attention to improving sleep hygiene.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.