ArticleBrain communications2020
Cohort study of electroencephalography markers of amyloid-tau-neurodegeneration pathology.
Article in Brain communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Tracking electrophysiological signatures of Alzheimer's disease: a systematic review of multimodal studies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- Peak alpha frequency and spectral exponent in postoperative delirium: a high-density EEG cohort study.BJA open · 2026Article
- EEG biomarkers can predict early-stage Alzheimer's disease and correlate with intracerebral pathology: a multimodal machine learning study.Alzheimer's research & therapy · 2026Article
- Electroencephalography for early Alzheimer's disease diagnosis: from advanced feature engineering to interpretable ai and clinical translation.Frontiers in psychiatry · 2026Review
- Resting-state EEG biomarkers of general and domain-specific cognitive impairment and plasma P-tau217 in patients with Alzheimer's disease and mild cognitive impairment.Frontiers in neurology · 2026Article
- Upconversion nanoparticle-FITC conjugate as a fluorescence switching probe for the sensitive detection of Tau: an Alzheimer's disease biomarker.Mikrochimica acta · 2025Article
- Resting-State EEG Alpha Rhythms Are Related to CSF Tau Biomarkers in Prodromal Alzheimer's Disease.International journal of molecular sciences · 2025Article
- Extracting interpretable signatures of whole-brain dynamics through systematic comparison.PLoS computational biology · 2024Article
- Neurophysiological and other features of working memory in older adults at risk for dementia.Cognitive neurodynamics · 2024Article
- Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer's disease.Molecular neurodegeneration · 2023Review
- Observational
- Reduced Electroencephalogram Complexity in Postoperative Delirium.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Association of Plasma and Electroencephalography Markers With Motor Subtypes of Parkinson's Disease.Frontiers in aging neuroscience · 2022Article
- Greater tau pathology is associated with altered predictive coding.Brain communications · 2022Article
- Relationships between preoperative cortical thickness, postoperative electroencephalogram slowing, and postoperative delirium.British journal of anaesthesia · 2021Article
- Combined 64-channel EEG and PET evaluation of lecanemab efficacy: Two case reports.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 4 countries.
Funding
Abstract
Electroencephalography signatures of amyloid-β, tau and neurodegenerative pathologies would aid in screening for, tracking progression of, and critically, understanding the pathogenesis of dementia. We hypothesized that slowing of the alpha peak frequency, as a signature of hyperpolarization-activated cyclic nucleotide gated 'pacemaker' channel activity, would correlate with amyloid and tau pathology burden measured by amyloid (Pittsburgh Compound B) and tau (MK-6240) positron emission tomography or CSF biomarkers. We also hypothesized that EEG power would be associated with neurodegeneration (CSF neurofilament light and hippocampal volume). Wakeful high-density EEG data were collected from 53 subjects. Both amyloid-β and tau pathology were associated with slowing in the alpha peak frequency [Pittsburgh Compound B (+) vs. Pittsburgh Compound B (-) subjects,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.