Evidence map›Paper›PMID 32954342›Full record

ArticleBrain communications2020

Cholinergic muscarinic M

Sean J Colloby, Pradeep J Nathan, Ian G McKeith, Geor Bakker, John T O'Brien, John-Paul Taylor

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. (Dis-)Connected Dots in Dementia with Lewy Bodies-A Systematic Review of Connectivity Studies.Movement disorders : official journal of the Movement Disorder Society · 2023
    Pooled it
  2. Article
  3. A spatial covarianceJournal of neurology · 2025
    Article
  4. Review
  5. Molecular connectivity studies in neurotransmission: a scoping review.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  6. Visual dysfunction in dementia with Lewy bodies.Current neurology and neuroscience reports · 2024
    Review
  7. Chemistry and Toxicology of Major Bioactive Substances inInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Sean J CollobyTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK.
Pradeep J NathanExperimental Medicine, Neuroscience Therapeutic Area, Sosei Heptares, Steinmetz Building, Granta Park, Cambridge CB21 6DG, UK.
Ian G McKeithTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK.
Geor BakkerExperimental Medicine, Neuroscience Therapeutic Area, Sosei Heptares, Steinmetz Building, Granta Park, Cambridge CB21 6DG, UK.
John T O'BrienDepartment of Psychiatry, University of Cambridge, Cambridge CB2 0QC, UK.
John-Paul TaylorTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK.
Newcastle Hospitals - Campus for Ageing and Vitality · GBUniversity of Cambridge · GBHeptares Therapeutics (United Kingdom) · GBNewcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholinergic dysfunction is central in dementia with Lewy bodies, possibly contributing to the cognitive and psychiatric phenotypes of this condition. We investigated baseline muscarinic M

Indexed as

cholinergicDementia with Lewy bodiesdonepezilM1/M4muscarinic receptors

Identifiers

PMID32954342
PMCPMC7475694
OpenAlexW3042981392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.