Evidence map›Paper›PMID 32954163›Full record

ArticleACS omega2020

Ultrathin and Robust Micro-Nano Composite Coating for Implantable Pressure Sensor Encapsulation.

Jialin Yao, Wenjiang Qiang, Hao Wei, Yan Xu, Bo Wang, Yushuang Zheng, Xizi Wang, Zequn Miao, Lejin Wang, Song Wang and 1 more

Abstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. The application of impantable sensors in the musculoskeletal system: a review.Frontiers in bioengineering and biotechnology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jialin YaoSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
Wenjiang QiangSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
Hao WeiSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
Yan XuSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
Bo WangSchool of Mechanical and Electrical Engineering, Yantai University, Yantai 264005, People's Republic of China.
Yushuang ZhengSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
Xizi WangSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.
Zequn MiaoCenter of Optometry, Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, People's Republic of China.
Lejin WangCenter of Optometry, Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, People's Republic of China.
Song WangThe State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing 100084, People's Republic of China.
Xing YangThe State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing 100084, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implantable pressure sensors enable more accurate disease diagnosis and real-time monitoring. Their widescale usage is dependent on a reliable encapsulation to protect them from corrosion of body fluids, yet not increasing their sizes or impairing their sensing functions during their lifespans. To realize the above requirements, an ultrathin, flexible, waterproof while robust micro-nano composite coating for encapsulation of an implantable pressure sensor is designed. The composite coating is composed of a nanolayer of silane-coupled molecules and a microlayer of parylene polymers. The mechanism and principle of the composite encapsulation coating with high adhesion are elucidated. Experimental results show that the error of the sensors after encapsulation is less than 2 mmHg, after working continuously for equivalently over 434 days in a simulated body fluid environment. The effects of the coating thickness on the waterproof time and the error of the sensor are also studied. The encapsulated sensor is implanted in an isolated porcine eye and a living rabbit eye, exhibiting excellent performances. Therefore, the micro-nano composite encapsulation coating would have an appealing application in micro-nano-device protections, especially for implantable biomedical devices.

Identifiers

PMID32954163
PMCPMC7495720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.