Evidence map›Paper›PMID 32954069›Full record

ArticleKidney international reports2020

Urinary Protein Biomarker Panel for the Diagnosis of Antibody-Mediated Rejection in Kidney Transplant Recipients.

Inge Mertens, Hanny Willems, Elisabet Van Loon, Karin Schildermans, Kurt Boonen, Geert Baggerman, Dirk Valkenborg, Wilfried Gwinner, Dany Anglicheau, Marie Essig and 2 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  4. Noninvasive Diagnosis of Kidney Allograft Rejection.Journal of the American Society of Nephrology : JASN · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Inge MertensHealth Unit, Centre for Proteomics, VITO, Mol, Belgium.
Hanny WillemsHealth Unit, Centre for Proteomics, VITO, Mol, Belgium.
Elisabet Van LoonDepartment of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Karin SchildermansHealth Unit, Centre for Proteomics, VITO, Mol, Belgium.
Kurt BoonenHealth Unit, Centre for Proteomics, VITO, Mol, Belgium.
Geert BaggermanHealth Unit, Centre for Proteomics, VITO, Mol, Belgium.
Dirk ValkenborgDepartment of Mathematics and Statistics, Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Belgium.
Wilfried GwinnerDepartment of Nephrology, Hannover Medical School, Hannover, Germany.
Dany AnglicheauDepartment of Nephrology and Kidney Transplantation, Adult Nephrology-Renal Transplant Service, Necker-Enfants Malades Hospital, Paris, France.
Marie EssigDepartment of Nephrology, CHU Limoges, Limoges, France.
Pierre MarquetDepartment of Nephrology, CHU Limoges, Limoges, France.
Maarten NaesensDepartment of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
University of Antwerp · BECentre Hospitalier Universitaire de Limoges · FRKU Leuven · BEHasselt University · BEHôpital Necker-Enfants Malades · FRMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAntibody-mediated rejection (ABMR) impacts kidney allograft outcome. The diagnosis is made based on findings from invasive kidney transplant biopsy specimens. The aim of this study was to identify a noninvasive urinary protein biomarker for ABMR after kidney transplantation.

methodsWe performed a multicenter case-control study to identify a urinary biomarker for ABMR (training cohort,

resultsWe identified a set of 10 urinary proteins that accurately discriminated patients with (

conclusionsWe identified and validated a urinary protein biomarker set that can be used to exclude ABMR.

Indexed as

antibody-mediated rejectionnoninvasive biomarkerrenal transplantationurinary proteomics

Identifiers

PMID32954069
PMCPMC7486186
OpenAlexW3039860847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.