Evidence map›Paper›PMID 32954050›Full record

ArticleBioactive materials2021

Reversing cold tumors to hot: An immunoadjuvant-functionalized metal-organic framework for multimodal imaging-guided synergistic photo-immunotherapy.

Zhijin Fan, Hongxing Liu, Yaohua Xue, Jingyan Lin, Yu Fu, Zhaohua Xia, Dongming Pan, Jian Zhang, Kun Qiao, Zhenzhen Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 174 citations in OpenAlex.

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  11. Targeted Drug Nanodelivery and Immunotherapy for Combating Tumor Resistance.Combinatorial chemistry & high throughput screening · 2025
    Review
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  13. Article
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  16. New Strategies for Macrophage Re-Education in Cancer: An Update.International journal of molecular sciences · 2024
    Review
  17. Article
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  20. Review

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Zhijin FanMolecular Diagnosis and Treatment Center for Infectious Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Hongxing LiuDepartment of Urology, Guangzhou Institute of Urology, Guangdong Key Laboratory of Urology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, 510230, China.
Yaohua XueMolecular Diagnosis and Treatment Center for Infectious Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Jingyan LinDepartment of Thoracic Surgery, Shenzhen Third People's Hospital, Shenzhen, 518110, China.
Yu FuDepartment of Thoracic Surgery, Shenzhen Third People's Hospital, Shenzhen, 518110, China.
Zhaohua XiaDepartment of Thoracic Surgery, Shenzhen Third People's Hospital, Shenzhen, 518110, China.
Dongming PanDepartment of Thoracic Surgery, Shenzhen Third People's Hospital, Shenzhen, 518110, China.
Jian ZhangDepartment of Biomedical Engineering, School of Basic Medical Science, Guangzhou Medical University, Guangzhou, 511436, China.
Kun QiaoDepartment of Thoracic Surgery, Shenzhen Third People's Hospital, Shenzhen, 518110, China.
Zhenzhen ZhangInstitute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, 510631, China.
Yuhui LiaoMolecular Diagnosis and Treatment Center for Infectious Diseases, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Shenzhen Third People’s Hospital · CNSouthern Medical University · CNFirst Affiliated Hospital of Guangzhou Medical University · CNGuangzhou Medical University · CNSouth China Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy assays using immunoadjuvants and tumor antigens could greatly increase the survival rates of patients with malignant tumors. As effective carriers, metal-organic frameworks (MOFs) have been widely utilized in cancer therapy due to their remarkable histocompatibility and low toxicity. Herein, we constructed a multimodal imaging-guided synergistic cancer photoimmunotherapy by employing a specific MOF (MIL101-NH

Indexed as

CpGHot tumorMetal-organic frameworksMultimodal imagingSynergistic cancer photoimmunotherapy

Identifiers

PMID32954050
PMCPMC7475520
OpenAlexW3082563097

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.