Evidence map›Paper›PMID 32953642›Full record

ArticlePediatric gastroenterology, hepatology & nutrition2020

Efficacy of the Probiotic Probiotical Confirmed in Acute Gastroenteritis.

Sandra Kluijfhout, Thanh-Van Trieu, Yvan Vandenplas

Registry-linked trialAbstract read
In one paragraph

Article in Pediatric gastroenterology, hepatology & nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06090708 (Effect of Mothers' Application of Yogurt Probiotic Bacteria on Relieving Their Young Children's Acute Gastroenteritis), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06090708 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Mothers' Application of Yogurt Probiotic Bacteria on Relieving Their Young Children's Acute Gastroenteritis

TypeinterventionalSponsorAlexandria UniversityRan2022 to 2023Enrolled60ConditionsAcute GastroenteritisArmsyogurt with probiotic bacteria
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Nutraceuticals and biotics in pediatric gastrointestinal disorders.European journal of clinical nutrition · 2024
    Review
  5. Acute Infectious Diarrhea.Advances in experimental medicine and biology · 2024
    Review
  6. Review
  7. Review
  8. Contribution ofLife (Basel, Switzerland) · 2022
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sandra KluijfhoutKidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.ORCID https://orcid.org/0000-0002-3595-1653
Thanh-Van TrieuCHL KannerKlinik, Urgences Pédiatriques, Luxembourg, Luxembourg.ORCID https://orcid.org/0000-0002-9550-3756
Yvan VandenplasKidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.ORCID https://orcid.org/0000-0002-1862-8651

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSome probiotic strains reduce the duration of acute diarrhea. Because of strain and product specificity, each product needs to be supported by clinical data. This study aimed to test the efficacy of the synbiotic food supplement Probiotical (

methodsA total of 46 children (aged 3.6 months to 12 years) with acute gastroenteritis that started less than 48 hours prior to their visit at a hospital-based emergency department were included in this prospective, randomized, placebo-controlled trial. All children were treated with oral rehydration solution and placebo (n=20) or the test product (n=26).

resultsSignificantly more children had a normal stool consistency on days 1 and 2 in the probiotic group: 5 children (20%) on day 1 in the probiotic group compared with none in the placebo group (

conclusionThe test product was shown to normalize stool consistency significantly more rapidly than the placebo. These data confirm the findings from a previous study in a larger group of children performed in a primary healthcare setting.

Indexed as

Acute gastroenteritisDiarrheaProbioticsSynbiotic

Identifiers

PMID32953642
PMCPMC7481057

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.