Evidence map›Paper›PMID 32953524›Full record

ArticleTranslational lung cancer research2020

Rates of positive lung cancer screening examinations in academic versus community practice.

Louise M Henderson, Leon Bacchus, Thad Benefield, Roger Huamani Velasquez, M Patricia Rivera

Open access · diamondAbstract read
In one paragraph

Article in Translational lung cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Updates in Lung Cancer Screening: A Decade of Evidence.Seminars in respiratory and critical care medicine · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Louise M HendersonDepartment of Radiology, The University of North Carolina, Chapel Hill, NC, USA.
Leon BacchusDepartment of Radiology, The University of North Carolina, Chapel Hill, NC, USA.
Thad BenefieldDepartment of Radiology, The University of North Carolina, Chapel Hill, NC, USA.
Roger Huamani VelasquezDepartment of Radiology, The University of North Carolina, Chapel Hill, NC, USA.
M Patricia RiveraThe University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
Evaluating Lung Cancer Screening Patterns and Outcomes through a North Carolina RegistryR01CA212014 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Louise Henderson · 2017 to 2026
$5.4M
NCI NIH HHS P30 CA016086NCI NIH HHS R01 CA212014
6 · The paper itself

Abstract

The benefits and harms of lung cancer screening reported in the National Lung Screening Trial (NLST) likely differ from those observed in academic and community settings. High rates of positive screening findings in the NLST led to the development of the Lung CT Screening Reporting and Data System (Lung-RADS) to standardize interpretation and reporting. We conducted a prospective observational study of lung cancer screening data from four lung cancer screening sites in North Carolina to compare prospective use of Lung-RADS in a real-world screened population versus Lung-RADS retrospectively applied to the NLST, and to determine if Lung-RADS assessment use differs in academic versus community settings. We included 4,037 screening examinations from 11/2014 to 12/2018 in academic and community sites and 75,126 NLST LDCT screening exams. On baseline screening exams, the proportion of positive LDCT exams was higher in community versus academic sites or the NLST (17.7%

Indexed as

Health facilitieslungmass screeningradiology

Identifiers

PMID32953524
PMCPMC7481616
OpenAlexW3039225061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.