Evidence map›Paper›PMID 32953486›Full record

ArticleTranslational lung cancer research2020

CD5 and CD6 as immunoregulatory biomarkers in non-small cell lung cancer.

Andrea Moreno-Manuel, Eloisa Jantus-Lewintre, Ines Simões, Fernando Aranda, Silvia Calabuig-Fariñas, Esther Carreras, Sheila Zúñiga, Yvonne Saenger, Rafael Rosell, Carlos Camps and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Translational lung cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

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  17. A novel seven-gene panel predicts the sensitivity and prognosis of head and neck squamous cell carcinoma treated with platinum-based radio(chemo)therapy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Andrea Moreno-ManuelMolecular Oncology Laboratory, Fundación para la Investigación del Hospital General Universitario de Valencia, Valencia, Spain.
Eloisa Jantus-LewintreMolecular Oncology Laboratory, Fundación para la Investigación del Hospital General Universitario de Valencia, Valencia, Spain.
Ines SimõesImmunoreceptors of the Innate and Adaptative System, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Fernando ArandaImmunoreceptors of the Innate and Adaptative System, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Silvia Calabuig-FariñasTRIAL Mixed Unit, Centro de Investigación Príncipe Felipe-Fundación para la Investigación del Hospital General Universitario de Valencia, Valencia, Spain.
Esther CarrerasImmunoreceptors of the Innate and Adaptative System, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Sheila ZúñigaUnidad de Medicina de Precisión en Oncología Traslacional, INCLIVA, Valencia, Spain.
Yvonne SaengerDepartment of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Rafael RosellCatalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain.
Carlos CampsMolecular Oncology Laboratory, Fundación para la Investigación del Hospital General Universitario de Valencia, Valencia, Spain.
Francisco LozanoImmunoreceptors of the Innate and Adaptative System, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Rafael SireraMolecular Oncology Laboratory, Fundación para la Investigación del Hospital General Universitario de Valencia, Valencia, Spain.
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESCentro de Investigacion Principe Felipe · ESUniversitat Politècnica de València · ESColumbia University · USHospital General Universitario De Valencia · ESINCLIVA Health Research Institute · ESInstitut Català d'Oncologia · ES

Funding

Applying pathomics to establish a biosignature for aggressive skin melanoma.R01CA260375 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Rui Chang, Yvonne Margaret Saenger · 2021 to 2026
$3.1M
FDA HHS R01 FD006108NCI NIH HHS R01 CA260375
6 · The paper itself

Abstract

backgroundThe study of immune surveillance in the tumour microenvironment is leading to the development of new biomarkers and therapies. The present research focuses on the expression of

methods

resultsPatients with higher

conclusionsOur data support further studies on

Indexed as

CD5CD6immune checkpointmelanomanon-small cell lung cancer (NSCLC)

Identifiers

PMID32953486
PMCPMC7481598
OpenAlexW3043188964

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.