Evidence map›Paper›PMID 32953400›Full record

ArticleIntensive care medicine experimental2020

The conundrum of using hyperoxia in COVID-19 treatment strategies: may intermittent therapeutic hyperoxia play a helpful role in the expression of the surface receptors ACE2 and Furin in lung tissue via triggering of HIF-1α?

Andreas Koch, Wataru Kähler, Sebastian Klapa, Bente Grams, Pieter-Jan A M van Ooij

Open access · goldAbstract read
In one paragraph

Article in Intensive care medicine experimental, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Oxy-Inflammation in Humans during Underwater Activities.International journal of molecular sciences · 2024
    Review
  3. Review
  4. The Challenges of OInternational journal of molecular sciences · 2022
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Andreas KochJoint Section of Maritime Medicine, Naval Institute of Maritime Medicine and Christian-Albrechts-University Kiel, Kiel, Germany.
Wataru KählerJoint Section of Maritime Medicine, Naval Institute of Maritime Medicine and Christian-Albrechts-University Kiel, Kiel, Germany.
Sebastian KlapaJoint Section of Maritime Medicine, Naval Institute of Maritime Medicine and Christian-Albrechts-University Kiel, Kiel, Germany.
Bente GramsJoint Section of Maritime Medicine, Naval Institute of Maritime Medicine and Christian-Albrechts-University Kiel, Kiel, Germany.
Pieter-Jan A M van OoijDiving Medical Center, Royal Netherlands Navy, Den Helder, and Respiratory Department of the Academic Medical Center, Amsterdam, the Netherlands.
Kiel University · DEAcademic Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID32953400
PMCPMC7490775
OpenAlexW3085866397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.