ReviewF1000Research2020
Obesity and Bone.
Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Gut microbiota-mediated regulation of skeletal development: A review of mechanistic analysis and interventional strategies.Journal of advanced research · 2026Review
- Obesity is associated with suppressed bone turnover: a systematic review and meta-analysis.Frontiers in physiology · 2026Review
- Application of machine learning on health examination data for predicting the decrease of bone mineral density.International journal of clinical and experimental pathology · 2025Article
- Association of the Chinese visceral adiposity index with marrow adiposity in postmenopausal females.Frontiers in endocrinology · 2025Article
- Weight-Adjusted Waist Index (WWI)-A Promising Anthropometric Indicator of Depressive Symptoms in Hospitalized Older Patients.Nutrients · 2024Article
- Genome-wide association study of osteoporosis identifies genetic risk and interactions with Dietary Approaches to Stop Hypertension diet and sugar-sweetened beverages in a Hispanic cohort of older adults.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Relative Contribution of Metabolic Syndrome Components in Relation to Obesity and Insulin Resistance in Postmenopausal Osteoporosis.Journal of clinical medicine · 2024Article
- Obesity and periodontitis: a comprehensive review of their interconnected pathophysiology and clinical implications.Frontiers in nutrition · 2024Review
- Fatty infiltration in the musculoskeletal system: pathological mechanisms and clinical implications.Frontiers in endocrinology · 2024Review
- Pharmacology and mechanisms of apigenin in preventing osteoporosis.Frontiers in pharmacology · 2024Review
- Article
- Is There an Association between BMI, Height, and Gender and Long-Bone Fractures during Childhood and Adolescence? A Large Cross-Sectional Population Study of 911,206 Subjects.Children (Basel, Switzerland) · 2023Article
- Association of bone mineral density with trichlorophenol: a population-based study.BMC musculoskeletal disorders · 2023Article
- Pharmacodynamic Material Basis and Potential Mechanism Study of Spatholobi Caulis in Reversing Osteoporosis.Evidence-based complementary and alternative medicine : eCAM · 2023Article
- Association of the visceral adiposity index with femur bone mineral density and osteoporosis among the U.S. older adults from NHANES 2005-2020: a cross-sectional study.Frontiers in endocrinology · 2023Article
- Differential bone metabolism and protein expression in mice fed a high-fat diet versus Daurian ground squirrels following natural pre-hibernation fattening.Journal of Zhejiang University. Science. B · 2022Article
- High-fat diet-induced obesity augments the deleterious effects of estrogen deficiency on bone: Evidence from ovariectomized mice.Aging cell · 2022Article
- Musculoskeletal effects of obesity and bariatric surgery - a narrative review.Archives of endocrinology and metabolism · 2022Review
- Obesity, Bone Loss, and Periodontitis: The Interlink.Biomolecules · 2022Review
- GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway.Journal of cellular and molecular medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity and osteoporosis are both common conditions with high rates of morbidity and mortality. There is a relationship between obesity and bone. There are multiple factors that influence the risk of fracture, including the quality of bone, the risk of falls, and the padding around the bone. These multiple factors partly explain the finding that obesity protects against fractures in some sites while increasing the risk in other parts of the body. While it is well known that increased weight builds bone, there are several mechanisms related to the obese state that make the bone more fragile. These include the increased production of bone marrow fat cells at the expense of bone-forming osteoblasts, an increase in inflammatory cytokines leading to the activation of bone-resorbing osteoclasts, mutations in the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.