Evidence map›Paper›PMID 32952552›Full record

ArticleJournal of toxicology2020

Herbicide Widespread: The Effects of Pethoxamid on Nonalcoholic Fatty Liver Steatosis

Anna Virginia Adriana Pirozzi, Antonietta Stellavato, Chiara Schiraldi, Mariateresa Giuliano

Open access · goldAbstract read
In one paragraph

Article in Journal of toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna Virginia Adriana PirozziDepartment of Experimental Medicine, Section of Biotechnology, Medical Histology and Molecular Biology, University of Campania "L. Vanvitelli", Via De Crecchio 7, 80131 Naples, Italy.
Antonietta StellavatoDepartment of Experimental Medicine, Section of Biotechnology, Medical Histology and Molecular Biology, University of Campania "L. Vanvitelli", Via De Crecchio 7, 80131 Naples, Italy.
Chiara SchiraldiDepartment of Experimental Medicine, Section of Biotechnology, Medical Histology and Molecular Biology, University of Campania "L. Vanvitelli", Via De Crecchio 7, 80131 Naples, Italy.
Mariateresa GiulianoDepartment of Experimental Medicine, Section of Biotechnology, Medical Histology and Molecular Biology, University of Campania "L. Vanvitelli", Via De Crecchio 7, 80131 Naples, Italy.ORCID https://orcid.org/0000-0002-7338-9200
University of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pethoxamid is a widespread herbicidal product, presenting itself as an extremely flexible active substance and with a high potential for use as an herbicide for preemergence. The emergence of multiple resistance in crops has been addressed using combinations of preemergence and postemergence herbicides in the same seeding-harvest cycle. A winning combination of pethoxamid and glyphosate mainly affected the acidobacteria population. Glyphosate scientific literature has demonstrated an observational link between herbicide exposure and liver disease in human subjects. Identifying and ranking the risk to the public that pethoxamid could exert on target organs has not been evaluated so far. Due to similarities to glyphosate, we did look at the effect of pethoxamid on impaired liver cells HepG2, using a nonalcoholic fatty liver disease (NAFLD) cell model

Identifiers

PMID32952552
PMCPMC7487099
OpenAlexW3083148427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.