Evidence map›Paper›PMID 32952357›Full record

ArticleActa Cardiologica Sinica2020

Atrial and Ventricular Response to Treatment of Premature Ventricular Complexes.

Yi-Sheng Chen, Wei-Di Chen, Yin-Huei Chen, Akbarshakh Akhmerov, Hsiang-Chi Wang, Kuan-Cheng Chang, Yen-Nien Lin

Open access · greenAbstract read
In one paragraph

Article in Acta Cardiologica Sinica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Yi-Sheng ChenDepartment of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Wei-Di ChenDepartment of Chinese Medicine.
Yin-Huei ChenDivision of Endocrinology and Metabolism, Department of Internal Medicine, China Medical University Hospital, China Medical University.
Akbarshakh AkhmerovSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
Hsiang-Chi WangManagement Office for Health Data, China Medical University Hospital, Taichung.
Kuan-Cheng ChangGraduate Institute of Clinical Medical Science, China Medical University.
Yen-Nien LinGraduate Institute of Clinical Medical Science, China Medical University.
Cedars-Sinai Medical Center · USChina Medical University · CNChina Medical University · TWFar Eastern Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPremature ventricular complexes (PVC) may cause ventricular dyssynchrony and lead to left atrium and ventricle mechanical abnormalities. Although ventricular cardiomyopathy due to PVCs has been well studied, little is known about atrial adaptation to PVCs.

objectivesTo assess atrial and ventricular responses to PVC therapy.

methodsAll patients with PVC burden > 5000 beats/day on Holter monitoring were enrolled. Baseline demographics, comorbidities, social habits, Holter parameters, and echocardiography profiles were recorded. Follow-up Holter electrocardiography (ECG) and echocardiography data were compared between PVC-treated and non-treated patients.

resultsTwo hundred and eighty-six patients were enrolled, of whom 139 received PVC treatment. Among the treated patients, 125 who underwent follow up Holter ECG or echocardiography were included in the final analysis. The mean follow-up times of Holter ECG and echocardiography were 9.40 ± 6.70 and 9.40 ± 5.52 months, respectively. Ventricular arrhythmic burden was significantly reduced in the treatment group (16.46% vs. 13.41%, p = 0.041) but was significantly increased in the observation group (7.58% vs. 14.95%, p = 0.032). A significant increase in left atrial (LA) diameter (36.94 mm vs. 39.46 mm, p = 0.025) and reduction in left ventricular ejection fraction (LVEF) (57.26% vs. 53.8%, p = 0.040) were noted in the observation group. There were no significant differences in supraventricular arrhythmic burden in the observation group and LA diameter and LVEF in the treatment group.

conclusionsPVC therapy effectively reduced ventricular arrhythmic burden in the treatment group on follow-up. Our data suggest that PVC treatment may prevent LA dilation and LVEF decline.

Indexed as

Antiarrhythmic agentCardiomyopathyLeft atriumLeft ventriclePremature ventricular complexRadiofrequency catheter ablation

Identifiers

PMID32952357
PMCPMC7490612
OpenAlexW3087426259

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.