Evidence map›Paper›PMID 32951437›Full record

ArticleAIDS care2021

Persistence of oral pre-exposure prophylaxis (PrEP) among adolescent girls and young women initiating PrEP for HIV prevention in Kenya.

Jean de Dieu Tapsoba, Sahar Z Zangeneh, Eline Appelmans, Siavash Pasalar, Kira Mori, Lily Peng, Janice Tao, Paul Drain, Gordon Okomo, Stanley Bii and 9 more

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Jean de Dieu TapsobaVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Sahar Z ZangenehVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Eline AppelmansVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Siavash PasalarVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Kira MoriVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Lily PengVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Janice TaoVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Paul DrainDepartment of Global Health, University of Washington, Seattle, WA, USA.
Gordon OkomoMinistry of Health, Nairobi, Kenya.
Stanley BiiUnited States Agency for International Development, Nairobi, Kenya.
James MukabiPATH, Nairobi, Kenya.
Stephanie ZobristPATH, Seattle, WA, USA.
Martha BradyPATH, Seattle, WA, USA.
Rael ObandaPATH, Kisumu, Kenya.
Daniel Oluoch MadiangPATH, Kisumu, Kenya.
Jane CoverPATH, Seattle, WA, USA.
Ann DuerrVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID 0000-0002-3399-2208
Ying Qing ChenVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Christopher Obong'oPATH, Kisumu, Kenya.
Fred Hutch Cancer Center · USProgram for Appropriate Technology in Health · USMinistry of Health · KEUnited States Agency for International Development · USUniversity of Washington · US

Funding

Predicting PrEP Uptake and Adherence Among Adolescent Girls and Young Women in Sub-Saharan Africa: Leveraging Programmatic and Clinical Trials Data - Administrative SupplementR01HD094682 · NICHD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI CHEN, YING QING, DUERR, ANN C · 2017 to 2021
$3.0M
NICHD NIH HHS R01 HD094682
6 · The paper itself

Abstract

The Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) Initiative aims to reduce HIV infections among adolescent girls and young women (AGYW) in Africa. Oral pre-exposure prophylaxis (PrEP) is offered through DREAMS in Kenya to eligible AGYW in high burden counties including Kisumu and Homa Bay. This study examines PrEP persistence among AGYW in high burden community-based PrEP delivery settings. We evaluated PrEP persistence among AGYW in the DREAMS PrEP program in Kisumu and Homa Bay using survival analysis and programmatic PrEP refill data collected between March through December 2017. Among 1,259 AGYW who initiated PrEP during the study period, the median persistence time in the program was 56 days (95% CI: 49-58 days) and the proportion who persisted 3 months later was 37% (95% CI: 34-40%). Persistence varied by county (

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisAdolescentFemaleHumansKenyaMentorsSexual BehaviorAnti-HIV AgentsAdolescent girls and young womenDREAMS InitiativeHIV preventionpersistencePrEP, survival analysis

Identifiers

PMID32951437
PMCPMC7981281
OpenAlexW3087385432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.