Evidence map›Paper›PMID 32951411›Full record

ReviewClinical and molecular hepatology2020

The lymphatic system in alcohol-associated liver disease.

Reiichiro Kondo, Yasuko Iwakiri

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical and molecular hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Reiichiro KondoSection of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Yasuko IwakiriSection of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Kurume University · JPYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The role of Kupffer cells in alcohol-induced liver diseaseR01AA025342 · NIAAA · YALE UNIVERSITY · PI IWAKIRI, YASUKO · 2017 to 2021
$1.9M
Hemodynamics and hepatic remodelingR01DK117597 · NIDDK · YALE UNIVERSITY · PI IWAKIRI, YASUKO · 2018 to 2021
$1.5M
Lymphatics in the liverR56DK121511 · NIDDK · YALE UNIVERSITY · PI IWAKIRI, YASUKO · 2019 to 2019
$430k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS R01 AA025342NIDDK NIH HHS R01 DK117597NIDDK NIH HHS R56 DK121511
6 · The paper itself

Abstract

The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.

Indexed as

Liver Diseases, AlcoholicLymphatic VesselsHumansLymphangiogenesisLymphatic SystemInflammationLymphangiogenesisLymphaticsVascular endothelial growth factor C

Identifiers

PMID32951411
PMCPMC7641555
OpenAlexW3087128267

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.