ArticleJournal of clinical hypertension (Greenwich, Conn.)2020
Association of optimal blood pressure with mortality in patients taking antihypertensive medications.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Association of socioeconomic status with prognosis in hypertensive patients over age 65: a cohort study in the community setting.BMJ open · 2024Article
- Impact of hypertension diagnosis on morbidity and mortality: a retrospective cohort study in primary care.BMC primary care · 2023Article
- The Korea National Health and Nutrition Examination Survey data linked Cause of Death data.Epidemiology and health · 2022Article
- Optimal combinations of systolic and diastolic blood pressure in Korea: A nationwide population-based cohort study.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Association of optimal blood pressure with mortality in patients taking antihypertensive medications.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the relationship between blood pressure (BP) and mortality in patients taking antihypertensive medications in the Korean using data from the 2007-2015 Korean National Health and Nutrition Examination Surveys. A total of 6601 patients aged 30-74 years were included. Systolic BP (SBP) and diastolic BP (DBP) were both divided into four groups as follows: SBP < 120, 120 ≤ SBP ≤ 129 130 ≤ SBP ≤ 139, and SBP ≥ 140; DBP < 70, 70 ≤ DBP ≤ 79, 80 ≤ DBP ≤ 89, and DBP ≥ 90. The survival rates and hazard ratios were evaluated using Kaplan-Meier curves and multivariable Cox regression analyses. To evaluate the predictability of all-cause mortality according to SBP and/or DBP, we calculated Harrell's concordance-index. The lowest DBP group had a high risk of mortality regardless of the SBP status. The group with DBP < 70 mm Hg and SBP ≥ 140 mm Hg showed the highest mortality. The discriminatory ability calculated using Harrell's C-indexes was greater for the combination of SBP and DBP compared to DBP or SBP alone. These results suggest that it is more effective to simultaneously evaluate the effect of SBP and DBP to predict mortality; clinicians should manage DBP < 70 mm Hg when treating hypertensive patients.
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