Evidence map›Paper›PMID 32951173›Full record

ArticleProgress in biomaterials2020

Development of tannic acid-enriched materials modified by poly(ethylene glycol) for potential applications as wound dressing.

Beata Kaczmarek, Olha Mazur, Oliwia Miłek, Marta Michalska-Sionkowska, Anna M Osyczka, Konrad Kleszczyński

Open access · hybridAbstract read
In one paragraph

Article in Progress in biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Evaluation of Polymeric Matrix Loaded with Melatonin for Wound Dressing.International journal of molecular sciences · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Beata KaczmarekDepartment of Biomaterials and Cosmetics Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7, 87-100, Toruń, Poland.ORCID http://orcid.org/0000-0002-2563-2376
Olha MazurDepartment of Biomaterials and Cosmetics Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7, 87-100, Toruń, Poland.
Oliwia MiłekDepartment of Biology and Cell Imaging, Faculty of Biology, Institute of Zoology and Biomedical Research, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland.
Marta Michalska-SionkowskaDepartment of Environmental Microbiology and Biotechnology, Faculty of Biology and Environmental Protection, Nicolaus Copernicus University, Lwowska 1, 87-100, Toruń, Poland.
Anna M OsyczkaDepartment of Biology and Cell Imaging, Faculty of Biology, Institute of Zoology and Biomedical Research, Jagiellonian University, Gronostajowa 7, 30-387, Kraków, Poland.ORCID http://orcid.org/0000-0003-2423-5114
Konrad KleszczyńskiDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149, Münster, Germany. konrad.kleszczynski@ukmuenster.de.ORCID http://orcid.org/0000-0002-1311-263X
Nicolaus Copernicus University · PLJagiellonian University · PLUniversity of Münster · DE

Funding

Deutsche Forschungsgemeinschaft KL2900/2-1Narodowe Centrum Nauki UMO-2016/21/B/NZ5/00217
6 · The paper itself

Abstract

The interests in the biomedical impact of tannic acid (TA) targeting production of various types of biomaterials, such as digital microfluids, chemical sensors, wound dressings, or bioimplants constantly increase. Despite the significant disadvantage of materials obtained from natural-based compounds and their low stability and fragility, therefore, there is an imperative need to improve materials properties by addition of stabilizing formulas. In this study, we performed assessments of thin films over TA proposed as a cross-linker to be used in combination with polymeric matrix based on chitosan (CTS), i.e. CTS/TA at 80:20 or CTS/TA at 50:50 and poly(ethylene glycol) (PEG) at the concentration of 10% or 20%. We evaluated their mechanical parameters as well as the cytotoxicity assay for human bone marrow mesenchymal stem cells, human melanotic melanoma (MNT-1), and human osteosarcoma (Saos-2). The results revealed significant differences in dose-dependent of PEG regarding the maximum tensile strength (σ

Indexed as

Poly(ethylene glycol)ProliferationRegenerationTannic acidWound dressing

Identifiers

PMID32951173
PMCPMC7544793
OpenAlexW3087536574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.