Evidence map›Paper›PMID 32950969›Full record

ArticleAging2020

Characterization of LncRNA SNHG22 as a protector of NKIRAS2 through miR-4492 binding in osteosarcoma.

Huo-Liang Zheng, Run-Ze Yang, Wen-Ning Xu, Tao Liu, Peng-Bo Chen, Xin-Feng Zheng, Bo Li, Lei-Sheng Jiang, Sheng-Dan Jiang

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. LncSNHGs: new targets in osteosarcoma.Cancer gene therapy · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Osteosarcoma in a ceRNET perspective.Journal of biomedical science · 2024
    Review
  7. Review
  8. Changes in the small noncoding RNA transcriptome in osteosarcoma cells.Journal of orthopaedic surgery and research · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Huo-Liang ZhengDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
Run-Ze YangDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
Wen-Ning XuDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
Tao LiuDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
Peng-Bo ChenDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
Xin-Feng ZhengDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
Bo LiDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
Lei-Sheng JiangDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
Sheng-Dan JiangDepartment of Clinic of Spine Center, Xinhua Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai 200082, China.
XinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many studies have revealed the function of long noncoding RNA (LncRNA) in regulating tumorigenesis of osteosarcoma (OS). As a subgroup of LncRNA, small nucleolar RNA host genes (SNHGs) have emerged as potentially important in OS. According to our recent findings, small nucleolar RNA host gene 22 (SNHG22) plays an important role in inhibiting the growth and metastasis of OS. However, the underlying mechanism of SNHG22 in regulating OS progression remains unknown. In this study, we confirmed that SNHG22 was downregulated in OS, and the overexpression of SNHG22 significantly inhibited OS progression

Indexed as

miR-4492NKIRAS2OSSNHG22

Identifiers

PMID32950969
PMCPMC7585113
OpenAlexW3087122931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.