Evidence map›Paper›PMID 32949176›Full record

ArticleThe oncologist2021

Targeted Therapy with Anlotinib for a Patient with an Oncogenic FGFR3-TACC3 Fusion and Recurrent Glioblastoma.

Yong Wang, Dandan Liang, Jimin Chen, Huan Chen, Rui Fan, Ye Gao, Yongsheng Gao, Rongjie Tao, Henghui Zhang

Registry-linked trialOpen access · greenAbstract readCase Reports
In one paragraph

Article in The oncologist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04004975 (Phase II Clinical Trials on Anlotinib for the Treatment of Recurrent Glioblastoma.), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04004975 phase1 / phase2unknown statusnot on this map

Phase II Clinical Trials on Anlotinib for the Treatment of Recurrent Glioblastoma.

TypeinterventionalSponsorShandong Cancer Hospital and InstituteRan2019 to 2021Enrolled50ConditionsRecurrent GlioblastomaArmsAnlotinib
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Efficacy of Anlotinib in Treating Progressive Glioblastoma: Insights From a Single-Center Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. RT-PCR assay to detectNeuro-oncology practice · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. FGFR3-TACCs3 Fusions and Their Clinical Relevance in Human Glioblastoma.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yong Wang *Departments of Neurosurgery, Shandong Cancer Hospital and Institute Affiliated to Shandong University, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, People's Republic of China.
Dandan Liang *Genecast Biotechnology Co., Ltd, Wuxi, People's Republic of China.
Jimin ChenGenecast Biotechnology Co., Ltd, Wuxi, People's Republic of China.
Huan ChenGenecast Biotechnology Co., Ltd, Wuxi, People's Republic of China.
Rui FanGenecast Biotechnology Co., Ltd, Wuxi, People's Republic of China.
Ye GaoDepartment of Neurosurgery, The People's Hospital of ZhangQiu Area, Jinan, People's Republic of China.
Yongsheng GaoDepartment of Pathology, Shandong Cancer Hospital and Institute Affiliated to Shandong University, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, People's Republic of China.
Rongjie TaoDepartments of Neurosurgery, Shandong Cancer Hospital and Institute Affiliated to Shandong University, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, People's Republic of China.ORCID 0000-0002-2080-1046
Henghui ZhangGenecast Biotechnology Co., Ltd, Wuxi, People's Republic of China.ORCID 0000-0002-2820-7447
Genecast (China) · CNShandong University · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a case of recurrent glioblastoma treated with anlotinib in this report. The patient was administered anlotinib 12 mg p.o. once every day (days 1-14, with a 21-day cycle) (anlotinib clinical study NCT04004975) and oral temozolomide chemotherapy 100 mg/m

Indexed as

GlioblastomaQuinolinesHumansIndolesMicrotubule-Associated ProteinsNeoplasm Recurrence, LocalReceptor, Fibroblast Growth Factor, Type 3anlotinibFGFR3 protein, humanIndolesMicrotubule-Associated ProteinsQuinolinesReceptor, Fibroblast Growth Factor, Type 3TACC3 protein, human

Identifiers

PMID32949176
PMCPMC7930428
OpenAlexW3087018809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.