Evidence map›Paper›PMID 32948813›Full record

ArticleScientific reports2020

Combining deep learning with 3D stereophotogrammetry for craniosynostosis diagnosis.

Guido de Jong, Elmar Bijlsma, Jene Meulstee, Myrte Wennen, Erik van Lindert, Thomas Maal, René Aquarius, Hans Delye

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Assessing Medical Student Attentional Bias in Unicoronal Craniosynostosis: An Eye-Tracking Study.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  4. Quantifying Sagittal Craniosynostosis Severity: A Machine Learning Approach With CranioRate.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
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  7. Review
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  16. UCSQ Method Applied on 3D Photogrammetry: Non-Invasive Objective Differentiation Between Synostotic and Positional Plagiocephaly.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2023
    Article
  17. Review
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  19. 3D Photography to Quantify the Severity of Metopic Craniosynostosis.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Guido de JongDepartment of Neurosurgery, Radboudumc, Nijmegen, The Netherlands. Guido.deJong@radboudumc.nl.
Elmar BijlsmaDepartment of Neurosurgery, Radboudumc, Nijmegen, The Netherlands.
Jene MeulsteeRadboudumc 3D Lab, Radboudumc, Nijmegen, The Netherlands.
Myrte WennenDepartment of Neurosurgery, Radboudumc, Nijmegen, The Netherlands.
Erik van LindertDepartment of Neurosurgery, Radboudumc, Nijmegen, The Netherlands.
Thomas MaalRadboudumc 3D Lab, Radboudumc, Nijmegen, The Netherlands.
René AquariusDepartment of Neurosurgery, Radboudumc, Nijmegen, The Netherlands.
Hans DelyeDepartment of Neurosurgery, Radboudumc, Nijmegen, The Netherlands.
Radboud University Medical Center · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Craniosynostosis is a condition in which cranial sutures fuse prematurely, causing problems in normal brain and skull growth in infants. To limit the extent of cosmetic and functional problems, swift diagnosis is needed. The goal of this study is to investigate if a deep learning algorithm is capable of correctly classifying the head shape of infants as either healthy controls, or as one of the following three craniosynostosis subtypes; scaphocephaly, trigonocephaly or anterior plagiocephaly. In order to acquire cranial shape data, 3D stereophotographs were made during routine pre-operative appointments of scaphocephaly (n = 76), trigonocephaly (n = 40) and anterior plagiocephaly (n = 27) patients. 3D Stereophotographs of healthy infants (n = 53) were made between the age of 3-6 months. The cranial shape data was sampled and a deep learning network was used to classify the cranial shape data as either: healthy control, scaphocephaly patient, trigonocephaly patient or anterior plagiocephaly patient. For the training and testing of the deep learning network, a stratified tenfold cross validation was used. During testing 195 out of 196 3D stereophotographs (99.5%) were correctly classified. This study shows that trained deep learning algorithms, based on 3D stereophotographs, can discriminate between craniosynostosis subtypes and healthy controls with high accuracy.

Indexed as

Deep LearningCase-Control StudiesCraniosynostosesFacial BonesHeadHumansImaging, Three-DimensionalInfantPhotogrammetry

Identifiers

PMID32948813
PMCPMC7501225
OpenAlexW3087269353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.