Evidence map›Paper›PMID 32948687›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Chemokine Signatures of Pathogen-Specific T Cells I: Effector T Cells.

Jens Eberlein, Bennett Davenport, Tom T Nguyen, Francisco Victorino, Kevin Jhun, Verena van der Heide, Maxim Kuleshov, Avi Ma'ayan, Ross Kedl, Dirk Homann

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

  1. Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Trial
  2. Article
  3. Nociceptor neurons shape antiviral immunity.Journal of neuroinflammation · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jens EberleinBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.ORCID 0000-0002-6268-1767
Bennett DavenportBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Tom T NguyenBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.ORCID 0000-0003-4222-4099
Francisco VictorinoBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Kevin JhunDiabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.ORCID 0000-0002-1677-2297
Verena van der HeideDiabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.ORCID 0000-0002-3602-4405
Maxim KuleshovDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029; and.ORCID 0000-0002-7812-7752
Avi Ma'ayanDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029; and.
Ross KedlDepartment of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Dirk HomannBarbara Davis Center for Childhood Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO 80045; dirk.homann@mssm.edu.ORCID 0000-0002-7622-5754
University of Colorado Anschutz Medical Campus · USIcahn School of Medicine at Mount Sinai · US

Funding

Data Coordination and Integration Center for LINCS-BD2KU54HL127624 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MA'AYAN, AVI, SCHURER, STEPHAN C · 2014 to 2019
$23.5M
UCHSC DIABETES ENDOCRINOLOGY RESEARCH CENTERP30DK057516 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI HUTTON, JOHN C · 2000 to 2010
$14.0M
TRAINING PROGRAM IN IMMUNOLOGYT32AI007405 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Laurel L Lenz, Raul Martin Torres · 1991 to 2026
$10.5M
Molecular Pathogenesis of Infectious DiseasesT32AI052066 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAN DYK, LINDA F. · 2002 to 2022
$2.3M
TRAINING PROGRAM IN INVESTIGATIVE GASTROENTEROLOGYT32DK007792 · NIDDK · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI CHO, JUDY H. · 2001 to 2016
$2.3M
Regulation of Pathogen-specific T Cell Immunity by Adenosine GenerationR01AI093637 · NIAID · UNIVERSITY OF COLORADO DENVER · PI HOMANN, DIRK · 2012 to 2016
$2.0M
Knowledge Management Center for Illuminating the Druggable GenomeU24CA224260 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MA'AYAN, AVI · 2018 to 2023
$1.5M
Maturation of established antiviral CD8 T cell memoryR21AG026518 · NIA · UNIVERSITY OF COLORADO DENVER · PI HOMANN, DIRK · 2005 to 2006
$343k
NCI NIH HHS U24 CA224260NHLBI NIH HHS U54 HL127624NIAID NIH HHS R01 AI093637NIAID NIH HHS T32 AI007405NIAID NIH HHS T32 AI052066NIA NIH HHS R21 AG026518NIDDK NIH HHS P30 DK057516NIDDK NIH HHS T32 DK007792
6 · The paper itself

Abstract

The choreography of complex immune responses, including the priming, differentiation, and modulation of specific effector T cell populations generated in the immediate wake of an acute pathogen challenge, is in part controlled by chemokines, a large family of mostly secreted molecules involved in chemotaxis and other patho/physiological processes. T cells are both responsive to various chemokine cues and a relevant source for certain chemokines themselves; yet, the actual range, regulation, and role of effector T cell-derived chemokines remains incompletely understood. In this study, using different in vivo mouse models of viral and bacterial infection as well as protective vaccination, we have defined the entire spectrum of chemokines produced by pathogen-specific CD8

Indexed as

AnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesChemokinesInfectionsMiceMice, Inbred BALB CMice, KnockoutChemokines

Identifiers

PMID32948687
PMCPMC7541659
OpenAlexW3087402673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.