Evidence map›Paper›PMID 32948657›Full record

ArticlePediatrics2020

Persistent Hypertension in Children and Adolescents: A 6-Year Cohort Study.

David C Kaelber, A Russell Localio, Michelle Ross, Janeen B Leon, Wilson D Pace, Richard C Wasserman, Robert W Grundmeier, Jennifer Steffes, Alexander G Fiks

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Article
  5. Persistence and determinants of blood pressure phenotypes according to office and ambulatory blood pressure measurements in youth.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  6. Physician-Pharmacist Collaborative Drug Therapy Management in Pediatric Hypertension.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023
    Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

David C KaelberComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois; david.kaelber@case.edu.
A Russell LocalioComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois.
Michelle RossComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois.
Janeen B LeonComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois.
Wilson D PaceComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois.
Richard C WassermanComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois.
Robert W GrundmeierComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois.
Jennifer SteffesComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois.
Alexander G FiksComparative Effectiveness Research through Collaborative Electronic Reporting Consortium Research Team, Elk Grove Village, Illinois.
American Academy of Pediatrics · USUniversity of Pennsylvania · USAmerican Academy of Family Physicians · USChildren's Hospital of Philadelphia · USMetroHealth Medical Center · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
National Center for Pediatric Practice Based Research & LearningP30HS021645 · AHRQ · AMERICAN ACADEMY OF PEDIATRICS · PI FIKS, ALEXANDER GABRIEL · 2012 to 2016
$599k
AHRQ HHS P30 HS021645NCATS NIH HHS UL1 TR002548
6 · The paper itself

Abstract

objectivesTo determine the natural history of pediatric hypertension.

methodsWe conducted a 72-month retrospective cohort study among 165 primary care sites. Blood pressure measurements from two consecutive 36 month periods were compared.

resultsAmong 398 079 primary care pediatric patients ages 3 to 18, 89 347 had ≥3 blood pressure levels recorded during a 36-month period, and 43 825 children had ≥3 blood pressure levels for 2 consecutive 36-month periods. Among these 43 825 children, 4.3% (1881) met criteria for hypertension (3.5% [1515] stage 1, 0.8% [366] stage 2) and 4.9% (2144) met criteria for elevated blood pressure in the first 36 months. During the second 36 months, 50% (933) of hypertensive patients had no abnormal blood pressure levels, 22% (406) had elevated blood pressure levels or <3 hypertensive blood pressure levels, and 29% (542) had ≥3 hypertensive blood pressure levels. Of 2144 patients with elevated blood pressure in the first 36 months, 70% (1492) had no abnormal blood pressure levels, 18% (378) had persistent elevated blood pressure levels, and 13% (274) developed hypertension in the second 36-months. Among the 7775 patients with abnormal blood pressure levels in the first 36-months, only 52% (4025) had ≥3 blood pressure levels recorded during the second 36-months.

conclusionsIn a primary care cohort, most children initially meeting criteria for hypertension or elevated blood pressure had subsequent normal blood pressure levels or did not receive recommended follow-up measurements. These results highlight the need for more nuanced initial blood pressure assessment and systems to promote follow-up of abnormal results.

Indexed as

AdolescentAge FactorsBlood Pressure DeterminationBody HeightChildChild, PreschoolConfidence IntervalsFemaleHumansHypertensionMaleReference ValuesRegression AnalysisRetrospective StudiesSex FactorsTime Factors

Identifiers

PMID32948657
PMCPMC7786824
OpenAlexW3087524293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.