Evidence map›Paper›PMID 32948646›Full record

ArticleImmunoHorizons2020

Acute IL-4 Governs Pathogenic T Cell Responses during

Barun Poudel, Matthew S Yorek, Lalita Mazgaeen, Scott A Brown, Thirumala-Devi Kanneganti, Prajwal Gurung

Open access · goldAbstract read
In one paragraph

Article in ImmunoHorizons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. More than malaria: ExploringCurrent research in parasitology & vector-borne diseases · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Barun PoudelIowa Inflammation Program, University of Iowa, Iowa City, IA 52242.
Matthew S YorekIowa Inflammation Program, University of Iowa, Iowa City, IA 52242.ORCID 0000-0002-4737-9367
Lalita MazgaeenIowa Inflammation Program, University of Iowa, Iowa City, IA 52242.ORCID 0000-0001-9467-3705
Scott A BrownDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.ORCID 0000-0002-6686-9695
Thirumala-Devi KannegantiDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.ORCID 0000-0002-6395-6443
Prajwal GurungIowa Inflammation Program, University of Iowa, Iowa City, IA 52242; prajwal-gurung@uiowa.edu.ORCID 0000-0002-7451-9433
University of Iowa · USSt. Jude Children's Research Hospital · US

Funding

Role of NLR Inflammasomes in Autoinflammatory Diseases and Host DefenseR01AR056296 · NIAMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KANNEGANTI, THIRUMALA-DEVI · 2008 to 2022
$5.9M
The Non-Inflammasome NLRs in Immunity and Host defenseR01AI124346 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Thirumala-Devi Kanneganti · 2016 to 2026
$5.8M
Inflammatory Caspases in Innate Immunity and InflammationR37AI101935 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Thirumala-Devi Kanneganti · 2017 to 2026
$4.9M
NLR signaling in colitis and colorectal tumorigenesisR01CA163507 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KANNEGANTI, THIRUMALA-DEVI · 2012 to 2020
$3.5M
Inflammatory Caspases in Innate Immunity and InflammationR01AI101935 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KANNEGANTI, THIRUMALA-DEVI · 2012 to 2016
$2.2M
Elucidating CD47-SHP1 biology to understand autoinflammatory disordersR21AI148904 · NIAID · UNIVERSITY OF IOWA · PI GURUNG, PRAJWAL · 2020 to 2021
$386k
NCI NIH HHS R01 CA163507NIAID NIH HHS R01 AI101935NIAID NIH HHS R01 AI124346NIAID NIH HHS R21 AI148904NIAID NIH HHS R37 AI101935NIAMS NIH HHS R01 AR056296
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansInterferon-gammaInterleukin-4Leishmania majorLeishmaniasis, CutaneousMiceMice, Inbred BALB CTh1 CellsTh2 CellsInterferon-gammaInterleukin-4

Identifiers

PMID32948646
PMCPMC7640617
OpenAlexW3087186815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.