Evidence map›Paper›PMID 32948625›Full record

ArticleGenetics2020

Defining the Boundaries of Polycomb Domains in

Sandip De, Natalie D Gehred, Miki Fujioka, Fountane W Chan, James B Jaynes, Judith A Kassis

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  5. ThebioRxiv : the preprint server for biology · 2025
    Article
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  7. Article
  8. Article
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  10. Mechanisms of Interaction between Enhancers and Promoters in ThreeInternational journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sandip DeEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 jkassis@mail.nih.gov mr.sandipde@gmail.com.ORCID 0000-0002-2859-7203
Natalie D GehredEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0002-7815-4881
Miki FujiokaDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Fountane W ChanEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0003-0888-1669
James B JaynesDepartment of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.ORCID 0000-0001-7943-794X
Judith A KassisEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 jkassis@mail.nih.gov mr.sandipde@gmail.com.ORCID 0000-0001-9268-3213
National Institutes of Health · USThomas Jefferson University · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

Insulators: Determinants of chromosome topology and regulatory interactionsR01GM117458 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI JAYNES, JAMES B · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM117458
6 · The paper itself

Abstract

Polycomb group (PcG) proteins are an important group of transcriptional repressors that act by modifying chromatin. PcG target genes are covered by the repressive chromatin mark H3K27me3. Polycomb repressive complex 2 (PRC2) is a multiprotein complex that is responsible for generating H3K27me3. In

Indexed as

AnimalsDrosophila melanogasterEnhancer Elements, GeneticHistonesInsulator ElementsPolycomb Repressive Complex 2HistonesPolycomb Repressive Complex 2ChIP-seqPcGPREtopological domain

Identifiers

PMID32948625
PMCPMC7648573
OpenAlexW3087206788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.