Evidence map›Paper›PMID 32948589›Full record

ArticleScience advances2020

Single-molecule imaging reveals control of parental histone recycling by free histones during DNA replication.

D T Gruszka, S Xie, H Kimura, H Yardimci

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
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  11. Single-Molecule Approaches to Study DNA Condensation.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  12. Review
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  17. Article
  18. Reduced histone gene copy number disruptsbioRxiv : the preprint server for biology · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

D T GruszkaThe Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.ORCID 0000-0003-1675-140X
S XieThe Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
H KimuraCell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan.ORCID 0000-0003-0854-083X
H YardimciThe Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. hasan.yardimci@crick.ac.uk.ORCID 0000-0001-5009-1391
The Francis Crick Institute · GBTokyo Institute of Technology · JP

Funding

Wellcome Trust FC001221
6 · The paper itself

Abstract

During replication, nucleosomes are disrupted ahead of the replication fork, followed by their reassembly on daughter strands from the pool of recycled parental and new histones. However, because no previous studies have managed to capture the moment that replication forks encounter nucleosomes, the mechanism of recycling has remained unclear. Here, through real-time single-molecule visualization of replication fork progression in

Indexed as

HistonesNucleosomesChromatin Assembly and DisassemblyDNA ReplicationSingle Molecule ImagingHistonesNucleosomes

Identifiers

PMID32948589
PMCPMC7500940
OpenAlexW3087133230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.