Evidence map›Paper›PMID 32948578›Full record

ArticleBMJ open2020

TRIPOD statement: a preliminary pre-post analysis of reporting and methods of prediction models.

Amir H Zamanipoor Najafabadi, Chava L Ramspek, Friedo W Dekker, Pauline Heus, Lotty Hooft, Karel G M Moons, Wilco C Peul, Gary S Collins, Ewout W Steyerberg, Merel van Diepen

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In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  11. Predicting the future for neonates with symptomatic congenital heart disease.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amir H Zamanipoor NajafabadiDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands a.h.zamanipoor_najafabadi@lumc.nl.ORCID 0000-0003-2400-2070
Chava L RamspekDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-7883-5927
Friedo W DekkerDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Pauline HeusCochrane Netherlands, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0002-6886-4652
Lotty HooftDutch Cochrane Centre (DCC), Julius Center for Health Sciences and Primary Care, University Medical Centre (UMC) Utrecht, Utrecht University, Utrecht, The Netherlands.
Karel G M MoonsDepartment of Epidemiology, Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands.
Wilco C PeulDepartment of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands.
Gary S CollinsNDORMS, Oxford University, Oxford, UK.
Ewout W SteyerbergDepartment of Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.
Merel van DiepenDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

Funding

Cancer Research UK 27294Cancer Research UK C49297/A29084
6 · The paper itself

Abstract

objectivesTo assess the difference in completeness of reporting and methodological conduct of published prediction models before and after publication of the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) statement.

methodsIn the seven general medicine journals with the highest impact factor, we compared the completeness of the reporting and the quality of the methodology of prediction model studies published between 2012 and 2014 (pre-TRIPOD) with studies published between 2016 and 2017 (post-TRIPOD). For articles published in the post-TRIPOD period, we examined whether there was improved reporting for articles (1) citing the TRIPOD statement, and (2) published in journals that published the TRIPOD statement.

resultsA total of 70 articles was included (pre-TRIPOD: 32, post-TRIPOD: 38). No improvement was seen for the overall percentage of reported items after the publication of the TRIPOD statement (pre-TRIPOD 74%, post-TRIPOD 76%, 95% CI of absolute difference: -4% to 7%). For the individual TRIPOD items, an improvement was seen for 16 (44%) items, while 3 (8%) items showed no improvement and 17 (47%) items showed a deterioration. Post-TRIPOD, there was no improved reporting for articles citing the TRIPOD statement, nor for articles published in journals that published the TRIPOD statement. The methodological quality improved in the post-TRIPOD period. More models were externally validated in the same article (absolute difference 8%, post-TRIPOD: 39%), used measures of calibration (21%, post-TRIPOD: 87%) and discrimination (9%, post-TRIPOD: 100%), and used multiple imputation for handling missing data (12%, post-TRIPOD: 50%).

conclusionsSince the publication of the TRIPOD statement, some reporting and methodological aspects have improved. Prediction models are still often poorly developed and validated and many aspects remain poorly reported, hindering optimal clinical application of these models. Long-term effects of the TRIPOD statement publication should be evaluated in future studies.

Indexed as

PrognosisHumansepidemiologygeneral medicine (see internal medicine)statistics & research methods

Identifiers

PMID32948578
PMCPMC7511612

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.