Evidence map›Paper›PMID 32948551›Full record

SynthesisBMJ open2020

Sex-specific differences in children attending the emergency department: prospective observational study.

Joany M Zachariasse, Dorine M Borensztajn, Daan Nieboer, Claudio F Alves, Susanne Greber-Platzer, Claudia M G Keyzer-Dekker, Ian K Maconochie, Ewout W Steyerberg, Frank J Smit, Henriëtte A Moll

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Adverse childhood experiences and preventive health care among rural US children: A cross-sectional examination of 2022 National Health Interview Survey data.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 6 countries.

Joany M ZachariasseDepartment of General Paediatrics, Erasmus MC- Sophia Children's Hospital, Rotterdam, The Netherlands.
Dorine M BorensztajnDepartment of General Paediatrics, Erasmus MC- Sophia Children's Hospital, Rotterdam, The Netherlands.
Daan NieboerDepartment of Public Health, Erasmus MC - University Medical Center, Rotterdam, The Netherlands.
Claudio F AlvesDepartment of Paediatrics, Emergency Unit, Hospital Professor Doutor Fernando da Fonseca, Amadora, Portugal.
Susanne Greber-PlatzerDepartment of Pediatrics and Adolescent Medicine, Medical University, Vienna, Austria.
Claudia M G Keyzer-DekkerDepartment of Pediatric Surgery, Erasmus MC- Sophia Children's Hospital, Rotterdam, The Netherlands.
Ian K MaconochieDepartment of Pediatric Emergency Medicine, Imperial College NHS Healthcare Trust, London, UK.
Ewout W SteyerbergDepartment of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands.
Frank J SmitDepartment of Paediatrics, Maasstad Hospital, Rotterdam, The Netherlands.
Henriëtte A MollDepartment of General Paediatrics, Erasmus MC- Sophia Children's Hospital, Rotterdam, The Netherlands h.a.moll@erasmusmc.nl.ORCID 0000-0001-9304-3322
Erasmus MC - Sophia Children’s Hospital · NLErasmus MC · NLGaustad Hospital · NOHospital Prof. Dr. Fernando Fonseca · PTImperial College Healthcare NHS Trust · GBLeiden University Medical Center · NLMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the role of sex in the presentation and management of children attending the emergency department (ED).

designThe TrIAGE project (TRiage Improvements Across General Emergency departments), a prospective observational study based on curated electronic health record data.

settingFive diverse European hospitals in four countries (Austria, The Netherlands, Portugal, UK).

participantsAll consecutive paediatric ED visits of children under the age of 16 during the study period (8-36 months between 2012 and 2015).

main outcome measuresThe association between sex (male of female) and diagnostic tests and disease management in general paediatric ED visits and in subgroups presenting with trauma or musculoskeletal, gastrointestinal and respiratory problems and fever. Results from the different hospitals were pooled in a random effects meta-analysis.

results116 172 ED visits were included of which 63 042 (54%) by boys and 53 715 (46%) by girls. Boys accounted for the majority of ED visits in childhood, and girls in adolescence. After adjusting for age, triage urgency and clinical presentation, girls had more laboratory tests compared with boys (pooled OR 1.10, 95% CI 1.05 to 1.15). Additionally, girls had more laboratory tests in ED visits for respiratory problems (pooled OR 1.15, 95% CI 1.04 to 1.26) and more imaging in visits for trauma or musculoskeletal problems (pooled OR 1.10, 95% CI 1.01 to 1.20) and respiratory conditions (pooled OR 1.14, 95% CI 1.05 to 1.24). Girls with respiratory problems were less often treated with inhalation medication (pooled OR 0.76, 95% CI 0.70 to 0.83). There was no difference in hospital admission between the sexes (pooled OR 0.99, 95% CI 0.95 to 1.04).

conclusionIn childhood, boys represent the majority of ED visits and they receive more inhalation medication. Unexpectedly, girls receive more diagnostic tests compared with boys. Further research is needed to investigate whether this is due to pathophysiological differences and differences in disease course, whether girls present signs and symptoms differently, or whether sociocultural factors are responsible.

Indexed as

Emergency Service, HospitalTriageAdolescentAustriaChildFemaleHumansInfantMaleNetherlandsObservational Studies as TopicPortugalepidemiologypaediatric A&E and ambulatory carepaediatrics

Identifiers

PMID32948551
PMCPMC7500294
OpenAlexW3087708720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.