ArticleBMC musculoskeletal disorders2020
Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: a real-world study.
Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05691751 (Blood Loss Assessment in the Limited Application of Tourniquet During Primary Unilateral TKA), which is not on this map. Cited by 13 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Blood Loss Assessment in the Limited Application of Tourniquet During Primary Unilateral TKA: a Randomized Controlled Study
Who cites it
13 citing papers in PubMed.
- Comparison of total blood loss between limited tourniquet use and conventional tourniquet use in total knee arthroplasty: a randomized controlled trial.BMC musculoskeletal disorders · 2024Trial
- Blood-conserving and therapeutic efficacy of intravenous tranexamic acid at different time points after primary total knee arthroplasty with tourniquet application: a randomised controlled trial.BMC musculoskeletal disorders · 2023Trial
- With or without a Tourniquet? A Comparative Study on Total Knee Replacement Surgery in Patients without Comorbidities.Medicina (Kaunas, Lithuania) · 2023Trial
- Effect of tourniquet use on blood loss, pain, functional recovery, and complications in robot-assisted total knee arthroplasty: a prospective, double-blinded, randomized controlled trial.Journal of orthopaedic surgery and research · 2022Trial
- Tourniquet use in primary total knee arthroplasty is associated with a hypercoagulable status: a prospective thromboelastography trial.International orthopaedics · 2021Trial
- Assessing Postoperative Pain in Patients Who Underwent Total Knee Arthroplasty Using an Automated Self-Logging Patient-Reported Outcome Measure Collection Device: Retrospective Cohort Study.JMIR human factors · 2025Article
- No difference in reoperation rates or aseptic loosening following cemented total knee arthroplasty with or without a tourniquet.Archives of orthopaedic and trauma surgery · 2025Article
- Article
- Enhanced Recovery after Surgery Rehabilitation Protocol in the Perioperative Period of Orthopedics: A Systematic Review.Journal of personalized medicine · 2023Review
- Tourniquet use in total knee arthroplasty and the risk of infection: a meta-analysis of randomised controlled trials.Journal of experimental orthopaedics · 2022Article
- Effects of Surgical Approach and Tourniquet Use on Patient-Reported Outcomes Following Total Knee Arthroplasty: A Pilot Randomized Clinical Trial.Orthopedic research and reviews · 2022Article
- Blood Loss in Primary Unilateral Total Knee Arthroplasty with Limited Tourniquet Application: A Randomized Controlled Trial.JB & JS open accessArticle
- Defining tourniquetless total knee arthroplasty: A systematic review.Journal of orthopaedicsReview
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Authors and funding
7 authors.
Funding
Abstract
backgroundIn an enhanced recovery after surgery program, a growing number of orthopedists are reconsidering the necessity of tourniquet use in total knee arthroplasty (TKA). However, the impact of tourniquet use on transfusion rate and postoperative length of stay (PLOS) in TKA remains controversial. Therefore, we carried out a study to investigate the effect of tourniquet application in routine primary TKA on transfusion rate and PLOS.
methodsWe analyzed data from 6325 patients who underwent primary unilateral TKA and divided them into two groups according to whether a tourniquet was applied during the procedure, and a tourniquet was used in 4902 and not used in 1423. The information for transfusion and PLOS was extracted from patients' electronic health records, and the data were analyzed with logistic and linear regression analyses.
resultsFollowing TKA, the transfusion rate and PLOS were 14.52% and 7.72 ± 3.54 days, respectively, in the tourniquet group, and 6.47% and 6.44 ± 3.48 days, respectively, in the no-tourniquet group. After adjusting for the different related variables, tourniquet use was significantly correlated with a higher transfusion rate (risk ratio = 1.888, 95% confidence interval (CI) 1.449-2.461, P < 0.001) and a longer PLOS (partial regression coefficient (B) = 0.923, 95%CI 0.690-1.156, P < 0.001).
conclusionsOur findings suggested that tourniquet use in routine primary TKA was related to a higher transfusion rate and a longer PLOS. The impact of tourniquet use on transfusion rate and PLOS should be taken into account in clinical practice.
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