Evidence map›Paper›PMID 32948073›Full record

ArticleBrain sciences2020

Dynamic Cerebral Autoregulation Post Endovascular Thrombectomy in Acute Ischemic Stroke.

Faheem Sheriff, Pedro Castro, Mariel Kozberg, Sarah LaRose, Andrew Monk, Elsa Azevedo, Karen Li, Sameen Jafari, Shyam Rao, Fadar Oliver Otite and 5 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Review
  8. Observational
  9. Individualized autoregulation-guided arterial blood pressure management in neurocritical care.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Review
  17. Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Review
  18. Article
  19. Effect of drug interventions on cerebral hemodynamics in ischemic stroke patients.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Faheem SheriffDepartment of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.ORCID 0000-0002-3875-6175
Pedro CastroDepartment of Clinical Neurosciences and Mental Health, Faculty of Medicine of University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0003-1401-2398
Mariel KozbergDepartment of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Sarah LaRoseDepartment of Neurocritical Care, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Andrew MonkDepartment of Neurocritical Care, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Elsa AzevedoDepartment of Clinical Neurosciences and Mental Health, Faculty of Medicine of University of Porto, 4200-319 Porto, Portugal.
Karen LiDepartment of Neurocritical Care, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Sameen JafariDepartment of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Shyam RaoDepartment of Neurocritical Care, Brown University, Providence, RI 02912, USA.
Fadar Oliver OtiteDepartment of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Ayaz KhawajaDepartment of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Farzaneh SorondDepartment of Stroke and Neurocritical Care, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-6127-0739
Steven FeskeDepartment of Neurocritical Care, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Can Ozan TanDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Henrikas VaitkeviciusDepartment of Neurocritical Care, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.ORCID 0000-0002-6075-247X
Brigham and Women's Hospital · USUniversidade do Porto · PTBrown University · USHarvard University · USNorthwestern University · USTexas Tech University · US

Funding

NINDS NIH HHS R01-NS0850
6 · The paper itself

Abstract

The development of the endovascular thrombectomy (EVT) technique has revolutionized acute stroke management for patients with large vessel occlusions (LVOs). The impact of successful recanalization using an EVT on autoregulatory profiles is unknown. A more complete understanding of cerebral autoregulation in the context of EVT may assist with post-procedure hemodynamic optimization to prevent complications. We examined cerebral autoregulation in 107 patients with an LVO in the anterior circulation (proximal middle cerebral artery (M1/2) and internal cerebral artery (ICA) terminus) who had been treated using an EVT. Dynamic cerebral autoregulation was assessed at multiple time points, ranging from less than 24 hours to 5 days following last seen well (LSW) time, using transcranial Doppler ultrasound recordings and transfer function analysis. Complete (Thrombolysis in Cerebral Infarction (TICI) 3) recanalization was associated with a more favorable autoregulation profile compared with TICI 2b or poorer recanalization (

Indexed as

dynamic cerebral autoregulationendovascular thrombectomystroketranscranial doppler ultrasound

Identifiers

PMID32948073
PMCPMC7564150
OpenAlexW3084803525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.