Evidence map›Paper›PMID 32948002›Full record

ArticleJournal of clinical medicine2020

Effect of Statin Use on the Clinical Manifestations, Laboratory Test Results and Outcome of Lyme Neuroborreliosis.

Katarina Ogrinc, Andrej Kastrin, Stanka Lotrič-Furlan, Petra Bogovič, Tereza Rojko, Tjaša Cerar-Kišek, Eva Ružić-Sabljić, Gary P Wormser, Franc Strle

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Cholesterol Contributes to Risk, Severity, and Machine Learning-Driven Diagnosis of Lyme Disease.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Katarina OgrincDepartment of Infectious Diseases, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-8134-749X
Andrej KastrinInstitute for Biostatistics and Medical Informatics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Stanka Lotrič-FurlanDepartment of Infectious Diseases, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.
Petra BogovičDepartment of Infectious Diseases, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.
Tereza RojkoDepartment of Infectious Diseases, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.
Tjaša Cerar-KišekInstitute for Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-4053-5590
Eva Ružić-SabljićInstitute for Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Gary P WormserDivision of Infectious Diseases, New York Medical College, Valhalla, NY 10595, USA.
Franc StrleDepartment of Infectious Diseases, University Medical Center Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-4163-0503
Ljubljana University Medical Centre · SIUniversity of Ljubljana · SINew York Medical College · US

Funding

Javna Agencija za Raziskovalno Dejavnost RS P3-0296
6 · The paper itself

Abstract

Statins have anti-inflammatory and potentially antimicrobial activity, but whether they have a beneficial effect on the course of infectious diseases is controversial. In this study, we assessed the impact of pre-existing statin use on the course and outcome of Lyme neuroborreliosis manifested as meningoradiculitis (Bannwarth's syndrome). One hundred and twenty three consecutive patients with Bannwarth's syndrome, of whom 18 (14.6%) were being treated with statins, were included in the study. To assess the influence of statin use on the course and outcome of the disease, univariate and multivariable analyses were performed. No statistically significant association was found between statin pre-treatment and the clinical manifestations, laboratory test results, and outcome of Bannwarth's syndrome. In conclusion, pre-existing use of statins did not significantly impact either the clinical presentation or the outcome of Bannwarth's syndrome.

Indexed as

Bannwarth’s syndromecourseLyme neuroborrelisisoutcomestatin

Identifiers

PMID32948002
PMCPMC7563736
OpenAlexW3084776029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.