Evidence map›Paper›PMID 32947990›Full record

ArticleJournal of functional biomaterials2020

Biocompatibility of α-Al

Akrivi Asimakopoulou, Ioannis Gkekas, Georgia Kastrinaki, Alessandro Prigione, Vasileios T Zaspalis, Spyros Petrakis

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akrivi AsimakopoulouChemical Process & Energy Resources Institute/Centre for Research and Technology Hellas, 57001 Thessaloniki, Greece.
Ioannis GkekasInstitute of Applied Biosciences/Centre for Research and Technology Hellas, 57001 Thessaloniki, Greece.
Georgia KastrinakiLaboratory of Inorganic Materials/Chemical Process & Energy Resources Institute/Centre for Research and Technology Hellas, 57001 Thessaloniki, Greece.
Alessandro PrigioneDepartment of General Pediatrics, Neonatology and Pediatric Cardiology University Clinic Düsseldorf, Heinrich Heine University, 40225 Düsseldorf, Germany.ORCID 0000-0001-9457-1952
Vasileios T ZaspalisLaboratory of Inorganic Materials/Chemical Process & Energy Resources Institute/Centre for Research and Technology Hellas, 57001 Thessaloniki, Greece.
Spyros PetrakisInstitute of Applied Biosciences/Centre for Research and Technology Hellas, 57001 Thessaloniki, Greece.ORCID 0000-0001-9094-3480

Funding

General Secretariat for Research and Technology 122General Secretariat for Research and Technology KRIPIS II ODYSSEUSHellenic Foundation for Research and Innovation 122
6 · The paper itself

Abstract

backgroundBiocompatible materials-topography could be used for the construction of scaffolds allowing the three-dimensional (3D) organization of human stem cells into functional tissue-like structures with a defined architecture.

methodsStructural characterization of an alumina-based substrate was performed through XRD, Brunauer-Emmett-Teller (BET) analysis, scanning electron microscopy (SEM), and wettability measurements. Biocompatibility of the substrate was assessed by measuring the proliferation and differentiation of human neural precursor stem cells (NPCs).

resultsα-Al

conclusionsOur work indicates the potential use of alumina for the construction of 3D engineered biosystems utilizing human neurons. Such systems may be useful for diagnostic purposes, drug testing, or biotechnological applications.

Indexed as

a-aluminabiocompatibilitydifferentiationhuman neural precursor cellsnanoporosityneuronprotein adsorptionwettability

Identifiers

PMID32947990
PMCPMC7563382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.