Evidence map›Paper›PMID 32947956›Full record

ArticleBiomolecules2020

Regulation of Poly(ADP-Ribose) Polymerase 1 Activity by Y-Box-Binding Protein 1.

Konstantin N Naumenko, Mariya V Sukhanova, Loic Hamon, Tatyana A Kurgina, Elizaveta E Alemasova, Mikhail M Kutuzov, David Pastré, Olga I Lavrik

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Poly ADP-ribose signaling is dysregulated in Huntington disease.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. YB-1 activating cascades as potential targets in KRAS-mutated tumors.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. NADNAR cancer · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. DNA Damage Response.Biomolecules · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Konstantin N NaumenkoInstitute of Chemical Biology and Fundamental Medicine, SB RAS, 630090 Novosibirsk, Russia.
Mariya V SukhanovaInstitute of Chemical Biology and Fundamental Medicine, SB RAS, 630090 Novosibirsk, Russia.
Loic HamonLaboratoire Structure-Activité des Biomolécules Normales et Pathologiques, University of Evry, INSERM U1204, Université Paris-Saclay, 91025 Evry, France.
Tatyana A KurginaInstitute of Chemical Biology and Fundamental Medicine, SB RAS, 630090 Novosibirsk, Russia.
Elizaveta E AlemasovaInstitute of Chemical Biology and Fundamental Medicine, SB RAS, 630090 Novosibirsk, Russia.
Mikhail M KutuzovInstitute of Chemical Biology and Fundamental Medicine, SB RAS, 630090 Novosibirsk, Russia.
David PastréLaboratoire Structure-Activité des Biomolécules Normales et Pathologiques, University of Evry, INSERM U1204, Université Paris-Saclay, 91025 Evry, France.
Olga I LavrikInstitute of Chemical Biology and Fundamental Medicine, SB RAS, 630090 Novosibirsk, Russia.ORCID 0000-0001-5980-8889
Institute of Chemical Biology and Fundamental Medicine · RUInserm · FRNovosibirsk State University · RU

Funding

Russian Foundation for Basic Research 20-34-70028Russian Science Foundation 19-14-00107UEVE Université Paris-Saclay CIR 2017
6 · The paper itself

Abstract

Y-box-binding protein 1 (YB-1) is a multifunctional positively charged protein that interacts with DNA or RNA and poly(ADP-ribose) (PAR). YB-1 is poly(ADP-ribosyl)ated and stimulates poly(ADP-ribose) polymerase 1 (PARP1) activity. Here, we studied the mechanism of YB-1-dependent PAR synthesis by PARP1 in vitro using biochemical and atomic force microscopy assays. PAR synthesis activity of PARP1 is known to be facilitated by co-factors such as Mg

Indexed as

Protein Processing, Post-TranslationalDNADNA DamageFluorescence PolarizationHeLa CellsHumansMagnesiumMicroscopy, Atomic ForceNucleic Acid ConformationNucleosomesPoly Adenosine Diphosphate RibosePoly (ADP-Ribose) Polymerase-1Protein BindingProtein MultimerizationY-Box-Binding Protein 1DNAMagnesiumNucleosomesPARP1 protein, humanPoly Adenosine Diphosphate RibosePoly (ADP-Ribose) Polymerase-1Y-Box-Binding Protein 1poly(ADP-ribose) polymerase 1protein poly(ADP-ribosyl)ationY-box-binding protein 1

Identifiers

PMID32947956
PMCPMC7565162
OpenAlexW3086233365

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.