Probing the Highly Disparate Dual Inhibitory Mechanisms of Novel Quinazoline Derivatives against

Fisayo A Olotu, Mahmoud E Soliman

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Polypharmacology-Driven Discovery and Design of Highly Selective, Dual and Multitargeting Inhibitors ofCurrent drug targets · 2024
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fisayo A OlotuMolecular Bio-Computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4001, South Africa.

Mahmoud E SolimanMolecular Bio-Computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4001, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amino Acid SequenceBacterial ProteinsBinding SitesCyclic AMP-Dependent Protein KinasesDrug DesignHydrogen BondingHydrophobic and Hydrophilic InteractionsMolecular Docking SimulationMycobacterium tuberculosisPrincipal Component AnalysisProtein BindingProto-Oncogene Proteins c-aktQuantum TheoryQuinazolinesSequence AlignmentThermodynamicsBacterial ProteinsCyclic AMP-Dependent Protein KinasesProto-Oncogene Proteins c-aktQuinazolinesdual-targetingmedicinal chemistrymulti-drug and extensively drug resistanceMycobacterium tuberculosisserine/threonine protein kinasesstructure-based design

Identifiers

PMID32947886

DOI10.3390/molecules25184247

PMCPMC7571077

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.