Evidence map›Paper›PMID 32947848›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Cerebral White Matter Lesions on Diffusion-Weighted Images and Delayed Neurological Sequelae after Carbon Monoxide Poisoning: A Prospective Observational Study.

Sangun Nah, Sungwoo Choi, Han Bit Kim, Jungbin Lee, Sun-Uk Lee, Young Hwan Lee, Gi Woon Kim, Sangsoo Han

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sangun NahDepartment of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14584, Korea.ORCID 0000-0003-2667-2211
Sungwoo ChoiDepartment of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14584, Korea.
Han Bit KimDepartment of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14584, Korea.
Jungbin LeeDepartment of Radiology, Soonchunhyang University Bucheon Hospital, Bucheon 14584, Korea.
Sun-Uk LeeDepartment of Neurology, Korea University Medical Center, Seoul 02841, Korea.ORCID 0000-0001-8660-7759
Young Hwan LeeDepartment of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14584, Korea.
Gi Woon KimDepartment of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14584, Korea.
Sangsoo HanDepartment of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14584, Korea.ORCID 0000-0002-9709-3332
Soonchunhyang University · KRKorea University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCarbon monoxide (CO) poisoning can result in delayed neurological sequelae (DNS). Factors predicting DNS are still controversial. This study aims to determine whether acute brain lesions observed using diffusion-weighted magnetic resonance imaging (MRI) following acute CO poisoning are related to the subsequent development of DNS.

methodsThis prospective study was conducted on patients with CO poisoning treated at a university hospital in Bucheon, Korea. From August 2016 to July 2019, a total of 283 patients visited the hospital because of CO poisoning. Exclusion criteria included age under 18 years, refusing hyperbaric oxygen therapy, refusing MRI, being discharged against medical advice, being lost to follow-up, having persistent neurological symptoms at discharge, and being transferred from another hospital 24 h after exposure.

resultsOf the 154 patients included in the final study, acute brain lesions on MRI (ABLM) were observed in 49 patients (31.8%) and DNS occurred in 30 patients (19.5%). In a logistic regression analysis, lower Glasgow coma scale score and higher exposure time were associated with DNS, and the presence of ABLM in white matter was significantly associated with DNS (OR 6.741; 95% CI, 1.843-24.660;

conclusionThe presence of ABLM in white matter was significantly related to the occurrence of DNS. Early prediction of the risk of developing DNS through MRI may be helpful in treating patients with CO poisoning.

Indexed as

carbon monoxide poisoningmagnetic resonance imagingneurotoxicitywhite matter

Identifiers

PMID32947848
PMCPMC7555258
OpenAlexW3085299968

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.