ArticlePsychoneuroendocrinology2020
Within-person changes in cancer-related distress predict breast cancer survivors' inflammation across treatment.
Article in Psychoneuroendocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Article
- Physical Inactivity Amplifies the Link Between Anxiety, Depression, and Neck Pain in Breast Cancer Survivors.Biomedicines · 2025Article
- Differences in Emotional Awareness Moderate Cytokine-Symptom Associations Among Breast Cancer Survivors.Brain, behavior, and immunity · 2025Article
- Couples in breast cancer survivorship: Daily associations in relationship satisfaction, stress, and health.Comprehensive psychoneuroendocrinology · 2024Article
- Distress and inflammation are independently associated with cancer-related symptom severity.Comprehensive psychoneuroendocrinology · 2024Article
- Turning stress into success: A festschrift in honor of Janice Kiecolt-Glaser.Comprehensive psychoneuroendocrinology · 2024Article
- You can't spell distress without stress: Expanding our perspective of the intersection between mental and physical health in cancer survivors.Comprehensive psychoneuroendocrinology · 2024Review
- Confirmatory validation of a brief patient-reported outcome measure assessing psychological distress in caregivers of malignant mesothelioma patients: the Mesothelioma Psychological Distress Tool-Caregivers.Frontiers in psychology · 2024Article
- Distress Disorder Histories Relate to Greater Physical Symptoms Among Breast Cancer Patients and Survivors: Findings Across the Cancer Trajectory.International journal of behavioral medicine · 2023Article
- Associations between fatigue and cellular metabolism in breast cancer patients: A longitudinal study.Psychoneuroendocrinology · 2022Article
- Boosting stress resilience using flexibility as a framework to reduce depression risk.Brain, behavior, & immunity - health · 2021Article
- A review and novel theoretical model of how negative emotions influence inflammation: The critical role of emotion regulation.Brain, behavior, & immunity - health · 2021Article
- Distress Trajectories in Black and White Breast Cancer Survivors: From Diagnosis to Survivorship.Psychoneuroendocrinology · 2021Article
- Temporal biobehavioral pathways from perceived stress to symptom burden in patients with cancer: A three-wave longitudinal cross-lagged panel network analysis to inform supportive care.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAmong breast cancer survivors, elevated inflammation has been linked to greater recurrence risk. Psychological processes, such as cancer-related distress, can pose threats to a survivor's longevity and wellbeing. Although distress can heighten inflammation, little is known about how fluctuations in distress during and after treatment impact a woman's own inflammation - the primary question of this study.
methodsBreast cancer survivors (n = 165, stages 0-III) completed a baseline visit before treatment and two follow-up visits 6 and 18 months after. At each visit, women completed the Impact of Events Scale to assess cancer-related distress, and a blood sample was collected to measure proinflammatory cytokines IL-6, TNF-α, IL-1β, and IL-8. This longitudinal study related fluctuations in survivor's own cancer-related distress (i.e., within-person effects), as well as average effects of cancer-related distress between survivors (i.e., between-person effects) to inflammatory changes across visits.
resultsWomen had elevated inflammation at visits where they expressed more cancer-related distress than what was typical. In contrast, the average cancer-related distress was not associated with inflammation.
conclusionLarger increases in a women's cancer-related distress was linked with higher inflammation across visits. Comparing a survivor's own cancer-related distress to her average levels may prove useful in identifying links between distress and inflammation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.